For a computer aided detection system of retinal lesions, optic disc (OD) detection is the first and the most importance. Since the OD is once detected then other clinical importance regions such as fovea or macula can easily be determined, and the OD shape is often used to evaluate abnormal retinal features for diagnosis of abnormalities such as hypertensive retinopathy. In this paper, an appr...

Optic Disc (OD) localization is an important pre-processing step that significantly simplifies subsequent segmentation of the OD and other retinal structures. Current OD localization techniques suffer from impractically-high computation times (few minutes/image). In this work, we present an ultrafast technique that requires less than a second to localize the OD. The technique is based on reduci...

Introduction: Introduction: Few studies have investigated the distribution of stress around implants. In this study the distribution of stress in bones around implants was investigated in five overdenture (OD) treatment designs including OD-1, OD-2, OD-3, OD-4 and OD-5. Materials and methods: The Catia modeling software was used in order to simulate the tooth/implant model and bone. First, the ...

PURPOSE Long-acting β2-agonists (LABAs) have demonstrated efficacy in patients with COPD in clinical trials. The purpose of this study was to assess the comparative efficacy of all available dosages of all LABA monotherapies using a network meta-analysis. METHODS A systematic literature review identified 33 randomized controlled trials of LABA monotherapies (salmeterol 50 μg twice daily [BID]...

let $g$ be a finite group and $pi(g)$ be the set of all the prime‎ ‎divisors of $|g|$‎. ‎the prime graph of $g$ is a simple graph‎ ‎$gamma(g)$ whose vertex set is $pi(g)$ and two distinct vertices‎ ‎$p$ and $q$ are joined by an edge if and only if $g$ has an‎ ‎element of order $pq$‎, ‎and in this case we will write $psim q$‎. ‎the degree of $p$ is the number of vertices adjacent to $p$ and is‎ ...

We investigated the optical properties of colloidal-synthesized ZnO spherical nanoparticles prepared from 1-octadecene (OD), a mixture of trioctylamine (TOA) and OD (1:10), and a mixture of trioctylphosphine oxide (TOPO) and OD (1:12). It is found that the green photoluminescence (PL) of samples from the mixture of TOA/ OD and TOPO/OD is largely suppressed compared with that from pure OD. Moreo...

Studies were conducted in rats to determine the effect of maternal diabetes and the consequent hyperglycemia on cardiovascular function in the offspring. Diabetes was induced in pregnant Wistar rats through streptozotocin injection (50 mg/kg). Cardiovascular parameters were measured in 2-mo-old offspring animals of diabetic (OD, n=12) and control rats (OC, n=8). Arterial pressure (AP), heart ra...

INTRODUCTION In a preceding trial comparing two different titration schemes, insulin degludec/insulin aspart (IDegAsp) showed good efficacy for achieving HbA1c <7% when administered twice daily (BID) in patients with uncontrolled type 2 diabetes (T2D). However, poor glycemic control persisted in a minority of patients. The current exploratory trial investigated the efficacy and safety of intens...

We assessed the blockade of the renin-angiotensin system (RAS) achieved with 2 angiotensin (Ang) antagonists given either alone at different doses or with an ACE inhibitor. First, 20 normotensive subjects were randomly assigned to 100 mg OD losartan (LOS) or 80 mg OD telmisartan (TEL) for 1 week; during another week, the same doses of LOS and TEL were combined with 20 mg OD lisinopril. Then, 10...