PURPOSE Enhanced drug exposure to the ocular surface typically relies on inclusion of viscosity-enabling agents, whereas delivery to the back of the eye generally focuses on invasive means, such as intraocular injections. Using our novel mucus-penetrating particle (MPP) technology, which rapidly and uniformly coats and penetrates mucosal barriers, we evaluated if such drug formulations could in...

lorazepam has in increasingly being used in our country in recent years. pharmacologically, lorazepam belongs to the benzodiazepines known for their wide neurotropic properties. there have been several studies on the side effects of the drug as stress disorders, tumors, preconvulsive activities in case of epileptic attacks, overdose, and behavioral problems, but little is known regarding the te...

purpose: to compare complications and motility of hydroxyapatite versus medpor ocular implants after enucleation at ahvaz imam hospital (from jan 2010 to jun 2011). methods: in a clinical trial, 50 patients scheduled for enucleation were randomly divided in two groups of 25 patients. group 1 underwent enucleation + hydroxyapatite (ha) and group 2 underwent enucleation + medor implant. all patie...

purpose: to introduce the importance and world prevalence of ocular leishmaniasis (ol), its clinical manifestations, and diagnostic and management features with more emphasis on iranian cases. methods: we reviewed all available articles published about ol during recent 50 years. results: ol is an ocular protozoal infection which is widespread in the world but is more common in developing countr...

The aim of this study was to evaluate the efficacy of a hyaluronic acid containing eye drop in ameliorating ocular surface pathology and discomfort in canine keratoconjunctivitis sicca (KCS). Twenty five dogs with KCS treated with a topical carbomer (CA)-based tear replacement gel were moved to treatment with a hyaluronic acid (HA)-containing tear replacement eye drop. Dogs were subject to a fu...

Ocular involvement in lymphoma is a relatively rare condition that can result from a primary intraocular lymphoma or an intraocular manifestation of systemic lymphoma. Lymphoma manifestations frequently masquerade as other more benign intraocular conditions including allergic or infectious conjunctivitis, uveitis, multiple evanescent white dot syndrome, acute retinal necrosis, or herpetic retin...

Given the importance of potato in the economy and people’s nutrition, as well as planting of disease-free seeds, it seems necessary to produce healthy seeds through tissue culture. This study was conducted during 2012-2013 at the Research Center of Agricultural University of Tajikistan aiming to evaluate the effect of different sizes of mini-tuber on yield and yield components of potato crop. A...