the objective of the present study was to prepare controlled release formulation of moxifloxacin hydrochloride ocular nanoparticles. the nanoparticles were prepared by solvent displacement method using eudragit rl 100 as a polymer. different formulations were prepared by varying the ratios of drug and polymer and varying the ratios of organic and aqueous phase. the formulations were evaluated i...

purpose : to determine the distribution of iris colors in the population of tehran and to assess possible associations between iris color and ocular disorder methods : through a stratified random cluster sampling approach, 160 clusters were selected in different municipality districts of tehran, and the approached households were invited to a clinic. after the initial interview, all participant...

rehabilitation of facial defects is a complex task, requiring an individualized design of the technique for each patient. the disfigurement associated with the loss of an eye may result in significant physical and emotional problems. various treatment modalities are available, one of which is the use of implants. although implant-supported orbital prosthesis has a superior outcome, it may not b...

sulfur mustard, a bifunctional alkylating agent, causes severe eye injury. the injury is a result of late inflammation, which is mediated by prostaglandins. theoretically, inhibition of prostaglandins by reagents such as indomethacine could result in alleviation of clinical adverse effects. in this study, the protective effect of topically applied indomethacine against sulfur mustard toxicity w...

objective the prevalence of syphilis is increasing in the world. although ocular syphilis is not a common presentation of syphilis, it occurs in 2.5 to 5% of patients with tertiary syphilis and less than 1% of patients with untreated late syphilis. patient we report a 58-year-old man presented with a 3-month history of decreased vision. he developed neurosensory detachment, retinitis and panuve...

dirofilariasis is caused by a filariid parasite of the genus dirofilaria. this zoonotic infection is spread by mosquito vector from animal to human. ocular dirofilariasis involving the eye and adnexa is rare. a nodule in the right eye had developed in a 20-year-old soldier from mazandaran province, north of iran. the mass was removed surgically and measured 5x5 mm. the specimen was identified o...

Introduction: Chronic renal disease compromises of several renal involvements and several causative risk factors such as debates mellitus, hypertension, and old age. Ocular involvement seems to be related to chronic renal failure and hemodialysis as indicated by different studies. The aim of this study was the evaluation of prevalence of ocular manifestation in hemodialysis patients of Hamadan ...

Acute myopia following use of some drugs is a relatively rare condition. Topiramate prescribed for seizure prophylaxis is one of these drugs. In this paper a case of acute transient myopia after taking topiramate is reported. The reported patient is a 28-year old woman who had no history of any eye disease. Following consumption of topiramate pill for one week, she had found blurred vision ...

a 65–yrs-old man referred for an ocular discomfort and red eye. the clinical diagnosis was leech in the left eye and its species confirmed as being limnatis nilotica . ocular leech infestation should be considered in patients with a history of swimming or washing their face in streams and lakes. attention should also be given to ocular leech infestation in the differential diagnosis of ocular t...