Ochratoxin A was detected as a natural contaminant for the first time. It was present in a corn sample.

Abstract The goal of this study is to identify the optimum conditions for ochratoxin A (OTA) biodegradation by supernatant Agaricus campestris strain. Plackett–Burman and Box–Behnken methods were used determine OTA degradation under various incubation conditions. method was planned through 16 varied experiments with 15 variants. three most potent variants, sucrose, yeast extract wheat bran, sel...

4 Dragan Kovačević, PhD, full professor, Faculty of Food Technology Osijek. J. J. Strossmayer University of Osijek, Franje Kuhača 20, Osijek, Croatia Introduction Ochratoxin A is a mycotoxin, a secondary metabolite produced by the mold of Aspergillus and Penicillium species. Regarding the fact that research indicate to its nephrotoxic, neurotoxic, mutagenic, carcinogenic, teratogenic and immuno...

Recently a species in the genus Talaromyces, a uniseriate species of Aspergillus section Nigri and an isolate each of two widespread species, Penicillium rubens and P. commune, were reported to produce ochratoxin A. This claim was based on insufficient biological and chemical data. We propose a list of criteria that need to be met before an unexpected mycotoxin producer is reported. There have ...

The fate of ochratoxin A in brewing was investigated by adding (3H)ochratoxin A to the raw materials at 1- and 10-mug/g levels during mashing in a conventional microbrewing process. The results indicated that large portions (28 to 39%) of the added toxin were recovered in spent grains, with less recovery in the yeast (8 to 20%) and beer (14 to 18%). About 38 and 12% of the added toxin at levels...

A laboratory-scale fermentor designed for solid-substrate fermentation was constructed and tested. Its capacity to produce ochratoxin under varied conditions was determined with wheat as substrate. Ochratoxin yields of 2,000 to 2,500 mug/g of wheat were regularly obtained, and occasionally yields as high as 4,000 mug/g were obtained. The most critical factor in the fermentation was initial subs...

Occurrence of citrinin and ochratoxin A in different feed ingredients and compound feeds was screened by accredited methods based on the indirect competitive enzyme-linked immunosorbent assay. High frequency co-occurrence of both toxins was found in wheat grain and processed sunflower seeds. Citrinin levels exceeded those of ochratoxin A in the majority of co-contaminated feed samples, and the ...

A purification method for ochratoxin A, using liquid-liquid extractions and a final cleanup by high-pressure liquid chromatography, is described.

A strain of Aspergillus ochraceus Wilhelm, isolated from poultry feed, produced both penicillic acid and ochratoxin A. Studies demonstrating the ability of this fungus to colonize poultry feed and produce these two mycotoxins under various temperatures and moistures indicated that the interaction was complex. The optimal temperature for conidial development did not vary with moisture, but accum...