Here we present a novel matrix-mimetic nanoassembly based on polysaccharides. Chitosan electrospun fiber networks are decorated with heparin-containing polyelectrolyte complex nanoparticles (PCNs) that present basic fibroblast growth factor (FGF-2), both stably adsorbed to the surfaces and released into solution. These FGF-2/PCN complexes can be released from the fibers with zero-order kinetics...

Gold atomic cluster based nanocomposites are important in the field of energy and sensing applications due to their interesting optical, electronic, chemical and catalytic properties. In the present study a chitosan stabilized gold atomic cluster nanocomposite was synthesised by a simple electrochemical technique based on the anodic dissolution of a gold electrode in the presence of a cationic ...

In this study, N,N-Dimethyl-N-Octyl chitosan was synthesized. Nanoparticles containing insulin were prepared using PEC method and were statistically optimized using the Box-Behnken response surface methodology. The independent factors were considered to be the insulin concentration, concentration and pH of the polymer solution, while the dependent factors were characterized as the size, zeta po...

Physically crosslinked hydrogels resulted from interaction between N,N,N-trimethyl chitosan chloride (N-Quaternized Chitosan) (NQC) and poly(acrylic acid) (PAA) were synthesized in different weight ratios (3:1), (1:1) and (1:3) taking the following codes Q3P1, Q1P1 and Q1P3, respectively. Characterization of the mentioned hydrogels was done using several analysis tools including; FTIR, XRD, SEM...

IN THE TITLE COMPOUND (SYSTEMATIC NAME 1,3,7-trimethyl-2,6-dioxo-7H-purin-9-ium hydrogen sulfate monohydrate), C(8)H(11)N(4)O(2) (+)·HSO(4) (-)·H(2)O, the crystal packing is stabilized through N-H⋯O and O-H⋯O hydrogen bonds.

Non-steroidal anti-inflammatory drugs (NSAIDs) are among the most common pharmaceuticals used worldwide. They widely detected in natural waters due to their persistence wastewater treatment, and removal is desirable management. As a contribution tackle this challenge, study explores magnetic quaternary chitosan-based nanosorbents for effective magnetically assisted of three NSAIDs (diclofenac, ...

BACKGROUND The production of protein drugs has recently increased due to advances in biotechnology, but their clinical use is generally limited to parenteral administration due to low absorption in non-parenteral administration. Therefore, non-parenteral delivery systems allowing sufficient absorption draw much attention. METHODS Microparticles (MP) were prepared using chitosan-4-thio-butylam...