We place the paper [Berger-Sellke] By Berger and Sellke in context of the discussion about the validity of p-values and alternative methods for quantifying evidence against a point null hypothesis. 1. Prologue: Quantifying Evidence against a Point null hypothesis Fisher's p-values are everywhere in empirical science. Quoting a recent provocative paper [1] which addressed the (ir)reproducibility...

The coronal magnetic field above a particular photospheric region will vanish at a certain number of points, called null points. These points can be found directly in a potential field extrapolation or their density can be estimated from Fourier spectrum of the magnetogram. The spectral estimate, which assumes that the extrapolated field is random, homogeneous and has Gaussian statistics, is fo...

Background Endometriosis is one of the most commonly encountered benign problems in gynaecology. It is frequently associated with chronic pelvic pain, dysmenorrhoea, menorrhagia and dyspareunia, which lead to infertility. We determined the possible association between CYP1A1 MspI and GSTM1 null polymorphism in the pathogenesis of endometriosis. MaterialsAndMethods Ninety seven cases of endometr...