results in this study, seven sirna molecules were rationally designed against the nucleoprotein gene and validated using various computational methods for silencing different strains of rsv. additionally, three effective sirna molecules targeting the overlapping region of m2/l mrna were designed. conclusions this approach provides insight and a validated strategy for chemical synthesis of an an...

RNA-nucleoprotein (RNP) complexes are pivotal to the regulation of gene expression. These multiprotein, multifunctional act as scaffolds, molecular platforms, hubs interaction between RNA and proteins. The past decade has seen an exponential increase in methodologies identify functionally characterize these complexes. In this review, we provide overview recent advances knowledge gained by chara...

Over half a million people in the United States have sys-temic lupus. Most are women in their childbearing years. They usually have arthritis and scarring rashes, and about half have kidney involvement that may progress to renal failure. With time, there is an increasing likelihood that the brain will be involved, often resulting in loss of cognitive ability, seizures, and psychosis. Although t...

We show that overloading is NP-complete. This solves exercise 6.25 in the 1986 version of the Dragon book.