نتایج جستجو برای: nuclear respiratory factor1
تعداد نتایج: 442247 فیلتر نتایج به سال:
Skeletal muscle overexpression of nuclear respiratory factor 1 increases glucose transport capacity.
Nuclear respiratory factor 1 (NRF-1) is a transcriptional activator of nuclear genes that encode a range of mitochondrial proteins including cytochrome c, various other respiratory chain subunits, and delta-aminolevulinate synthase. Activation of NRF-1 in fibroblasts has been shown to induce increases in cytochrome c expression and mitochondrial respiratory capacity. To further evaluate the rol...
A lymphocyte blastogenesis inhibitory factor (LBIF) has been char acterized as an immunoregulatory molecule, especially on the T-lymphocyte proliferation. Using fast protein liquid chromatography-purified LBIF, we examined the effect of LBIF on the proliferation of various 18 tumor cell lines in vitro in comparison with those of interferon-a, interferon-7, tumor necrosis factor-a, transforming ...
C ellular mitochondria play important roles in the production of energy required by human cells, thermogenesis, calcium and iron homeostasis, innate immune responses, production of reactive oxygen species, and programmed cell death (apoptosis). Approximately 1000 nuclear genes encoding mitochondrial proteins have been identified to date. A mutation in any of these genes has the potential to giv...
Codon bias refers to the differences in the frequency of occurrence of synonymous codons in coding DNA. Pattern of codon and optimum codon utilization is significantly different between the lives. This difference is due to the long term function of natural selection and evolution process. Genetics drift, mutation and regulation of gene expression are the main reasons for codon bias. In this stu...
Background: The aim of the current study was to assess the mRNA levels of two mitochondria-related genes, including nuclear-encoded NRF1 (nuclear respiratory factor 1), mitochondrial transcription factor A (TFAM), and mitochondrial-encoded cytochrome c oxidase subunit 1 (MT-CO1) genes in various stages of the human oocyte maturation. Methods: Oocytes were obtained from nine infertile women wit...
مقدمه. سندرم زجرتنفسی نوزادان (infant respiratory distress syndrome) ، یک بیماری حاد ریوی است که معمولا نوزادان نارس به آن مبتلا می شوند. در این بیماری، ریه نابالغ و غیر عملکردی است. در واقع نقص در سورفاکتانت باعث ایجاد این بیماری می شود. سورفاکتانت باعث کاهش کشش سطحی آلوئول ها می شود و در نتیجه از کلاپس و بسته شدنشان جلوگیری می کند. پروتئین abca3 ترنسپورتر لیپیدهای سورفاکتانت، نقش بسیار مهمی د...
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