OBJECTIVE To inoculate white-tailed deer (Odocoileus virginianus) during the sixth or seventh week of gestation with bovine viral diarrhea virus (BVDV) and observe for signs of reproductive tract disease during a 182-day period. ANIMALS 10 pregnant white-tailed deer (8 seronegative and 2 seropositive [control deer] for BVDV). PROCEDURES Deer were inoculated with 1 of 2 deer-derived BVDV str...

Bovine viral diarrhoea virus (BVDV) is an endemic pathogen worldwide and eradication strategies focus on the identification and removal of persistently infected (PI) animals arising after in utero infection. Despite this, acute infections with BVDV can persist for months or years after the removal of the PI source despite repeated screening for PIs and tight biosecurity measures. Recent evidenc...

A noncytopathic type 1a bovine viral diarrhea virus (BVDV) was isolated from a free-ranging yearling female mule deer (Odocoileus hemionus) from northwestern Wyoming (USA). The mule deer was emaciated, weak, and salivating, and Arcanobacterium pyogenes was cultured from lung abscesses. Bovine viral diarrhea virus was isolated from lung, however, BVDV antigen was not detected by immunohistochemi...

Background and Aims: Sistan is a major pole in dairy production and genetic resource for the unique sistanian breed in the southeast of Iran. This region has a wide border with Afghanistan and cattle imports are done through this border.  The   main aim of this study was to compare the seroprevalence of Bovine Viral Diarrhea Virus (BVDV) infection rate using direct Enzyme-linked ...

bvdv and bhv-1 are considered as worldwide, complicated and economically significant infections associated with a range of clinical syndromes in cattle. as clinical syndromes such as pneumonia, diarrhea, abortion and reproductive losses were repeatedly reported in dairy herds in suburbs of arak, this study was planned to determine the prevalence of antibodies to bvdv and bhv-1 in industrial dai...

Abstract Studies of immune responses elicited by bovine viral diarrhea virus (BVDV) vaccines have primarily focused on the characterization neutralizing B cell and CD4+ T epitopes. Despite availability commercial for decades, BVDV prevalence in cattle has remained largely unaffected. There is limited knowledge regarding role BVDV-specific CD8+ cells protection, indirect evidence suggests that t...

Bovine viral diarrhea virus (BVDV) is an economically important pathogen of the livestock industry worldwide. BVDV is classified into cytopathic (cp) and noncytopathic (ncp), depending on its effects on cultured cells. BVDV is known to alter the host’s immune response. Of this, major histocompatibility complex (MHC) class II molecules play a central role in the development and function of the i...

The onset of protection after the administration of a modified-live bovine viral diarrhea virus (BVDV) vaccine was determined. Protection was determined following experimental infection with a virulent type-2 BVDV (strain 1373) in cattle vaccinated 3, 5, or 7 days before BVDV infection. Protection, as measured by reduced virus shedding, lack of leukopenia, reduction in viremia, and reduced mort...

To gain further insight into the genomic features of bovine viral diarrhea virus 1 (BVDV-1) subgenotypes, we sequenced the complete genome of BVDV-1n Shitara/02/06 and BVDV-1o IS26NCP/01. The complete genome of Shitara/02/06 and IS26NCP/01 shared 77.7 to 79.3% and 78.0 to 85.7% sequence identities with other BVDV-1 subgenotype strains, respectively.

BACKGROUND Vaccination of young calves against Bovine viral diarrhea virus (BVDV) is desirable in dairy and beef operations to reduce clinical disease and prevent spread of the virus among cattle. Although protection from clinical disease by multivalent, modified-live virus (MLV) vaccines has been demonstrated, the ability of MLV vaccines to prevent viremia and viral shedding in young calves po...