BACKGROUND Transverse myelitis has been reported in association with vaccination, including influenza vaccination. OBJECTIVE To describe a case of longitudinally extensive transverse myelitis associated with vaccination with a nasal attenuated novel influenza A(H1N1) vaccine. DESIGN Case report. SETTING Sanford University of South Dakota Hospital. Patient A 27-year-old woman with longitud...

a retrospective cohort study, in the context of household transmission, to estimate the serial interval (si) of ph1n1 influenza in the island of tierra del fuego was carried out.we collected data from the epidemiological surveillance system during disease outbreak in ushuaia and rio grande, the two main cities of the southernmost province of argentina. only the records of patients and household...

background: influenza virus is a major infectious pathogen of the respiratory system causing a high degree of morbidity and mortality annually. the worldwide vaccines are decided and produced annually by world health organization and licensed companies based on the samples collected from all over the world. the aim of this study was to determine phylogenecity and heterogenecity of the circulati...

Whereas in Europe and North America most of the influenza cases are reported between December and March, in tropical and subtropical regions such as in Brazil [1] or in Hong Kong [2] cases are seen throughout the year. Epidemic peaks in the tropical areas mostly occur in between those found in the Northern and Southern hemispheres. A recent survey over 7 years in Brazil showed that annual peaks...

Recent reports of mild to severe influenza-like illness in humans caused by a novel swine-origin 2009 A(H1N1) influenza virus underscore the need to better understand the pathogenesis and transmission of these viruses in mammals. In this study, selected 2009 A(H1N1) influenza isolates were assessed for their ability to cause disease in mice and ferrets and compared with a contemporary seasonal ...

background: a new pandemic influenza a (h1n1) emerged in april 2009, causing considerable morbidity and mortality. since mutations in the haemagglutinin (ha) may influence the antigenicity and pathogenicity of the virus, continued epidemiological and molecular characterization for the effective control of pandemic flu and developing of more appropriate vaccine is crucial. objective: to monitor ...

Host responses play crucial roles in defense against influenza but sometimes these may contribute to immunopathology. Potentially, this may be more important in disease caused by viruses such as avian influenza A H5N1 or the 1918 H1N1 influenza virus rather than with seasonal influenza or pandemic H1N1 2009 (pdmH1N1). Understanding pathogenesis will help develop novel therapeutic options that m...

results: of 655 samples, 69 (10.53%) had positive results for human influenza a virus, and 5 (0.7%) samples had positive results for influenza b. of those 69 samples with positive results for influenza a viruses, 45 (6.8%) were h3n2, and 24 (3.6%) were h1n1 subtypes. in this study most cases with positive results were less than 20 years. the sample positive included 49% males and 51% females. t...

conclusions: among confirmed patients with influenza a (h1n1), the most common symptoms were sequentially cough, dyspnea, chill and myalgia. pcr did not show high sensitivity in diagnosis of influenza a (h1n1) infection. the risk factor with the highest prevalence was heart disease followedby cigarette smoking and hematologic disorder. the mean age of these patients was about 38. results: rt pc...

BACKGROUND The 2009 novel A(H1N1) virus appears to be of swine origin. This strain causing the current outbreaks is a new virus that has not been seen previously either in humans or animals. We have previously reported that viruses causing pandemics or large outbreaks were able to grow at a temperature above the normal physiological range (temperature resistance, non-ts phenotype), were found t...