A 35-year-old male was referred because of eczema on the arms and lips that occurred episodically. He worked in a drug-manufacturing plant, and noticed that the episodes of eczema coincided with the production cycles of thebaine (CAS no. 115-37-7) and oripavine (CAS no. 467-04-9), but not with the production cycles of morphine (CAS no. 57-27-2) and noscapine (CAS no. 128-62-1). The eczema start...