ObjectiveTo investigate microRNA (miRNA) expression profiles in the seminal plasma of nonobstructive azoospermia (NOA) patients with different histopathologic patterns and evaluate potential noninvasive diagnostic biomarkers NOA.DesignSequencing validation using quantitative reverse transcription polymerase chain reaction (qRT-PCR).SettingReproductive center research institute.Patient(s)Thirtee...

OBJECTIVE To evaluate the relationship between duration of sexual abstinence and various characteristics of normal and subnormal semen. DESIGN A retrospective study based on computerized data. SETTING Fertility and IVF unit at a university medical center. PATIENT(S) Nine thousand, four hundred eighty-nine semen samples from 6,008 patients were analyzed according to the World Health Organi...

We have observed that sperm quality parameters indicative of spermatozoa hyperactivation such are lower "linearity" and "straightness", and as showed by this research "elongation", were more pronounced in patients with normal spermiogram compared to the group of men with reduced sperm motility who were undergoing routine in vitro fertilisation. The research encompassed 97 men diagnosed with nor...

Background Chlamydia trachomatis (CT) with damaging effects on sperm quality parameters can often cause infertility in men. Objective The main objective of this study was to determine the diagnostic value of polymerase chain reaction (PCR) and enzyme linked immuno sorbent assay (ELISA) for screening and detecting CT in semen samples of infertile men. Materials and Methods In this cross-sect...

BACKGROUND There is growing evidence that damage to spermatozoa by reactive oxygen species (ROS) play a key role in male infertility. The aim of the present study was to assess seminal plasma levels of total antioxidant capacity (TAC), free 8-Isoprostane and activities of catalase and superoxide dismutase (SOD) in men with asthenozoospermia, asthenoteratozoospermia and oligoasthenoteratozoosper...

AIM To assess seminal plasma anti-Müllerian hormone (AMH) level relationships in fertile and infertile males. METHODS Eighty-four male cases were studied and divided into four groups: fertile normozoospermia (n = 16), oligoasthenoteratozoospermia (n = 15), obstructive azoospermia (OA) (n = 13) and non-obstructive azoospermia (NOA) (n = 40). Conventional semen analysis was done for all cases. ...

Background: Telomeres are particular sequences of DNA located at the end of the eukaryotic chromosomes that are essential for genome integrity. Telomere length in spermatozoa differs among males, as well as spermatozoa. Also, decreased telomere length in spermatozoa of infertile men is associated with the reduction of fertility potential and embryo quality. Density gradient centrifugation (DGC)...

Abstract Introduction Clomiphene citrate (CC), a selective estrogen receptor modulator, and anastrozole, aromatase inhibitor, are common empiric medical therapies for men with idiopathic infertility. The effects of jointly administering these agents not well understood. Objective objective this study is to compare semen parameters in treated clomiphene anastrozole (CC-A) combination therapy tho...

Testicular cancer survival rates have increased to 95%, leading fatherhood becoming a major concern in half of male survivors. Since is not possible predict how chemotherapy (CT) will affect spermatogenesis, sperm cryopreservation before treatment highly recommended. It also unknown whether there an increase the rate chromosomal or epigenetic abnormalities post-CT sperm. Therefore, use fresh st...

background: there is growing evidence that damage to spermatozoa by reactive oxygen species (ros) play a key role in male infertility. objective: the aim of the present study was to assess the antioxidant status of seminal plasma by measuring total antioxidant capacity (tac) and activities of catalase and superoxide dismutase (sod) in men with asthenozoospermia, asthenoteratozoospermia and olig...