non-binding fraction and the composition of amniotic fluid altered accordingly. This is apparently so. Since affinity chromatography is more complicated than conventional AFP assay it will probably be used on selected samples. If the method proves as reliable as suggested here, an appropriate strategy would be to lower the cut-off value to three standard deviations above the mean total AFP conc...

Somatic genomic mutations in lung adenocarcinomas (LUADs) have been extensively dissected, but whether the counterpart normal lung tissues that are exposed to ambient air or tobacco smoke as the tumor tissues do, harbor genomic variations, remains unclear. Here, the genome of normal lung tissues and paired tumors of 11 patients with LUAD were sequenced, the genome sequences of counterpart norma...

PURPOSE Our purpose was to determine the variation in location, distribution, and sex predilection of arytenoid cartilage sclerosis in a population of patients without laryngeal cancer as an aid to understanding the significance of this entity when seen in patients with laryngeal cancer. METHODS One hundred CT examinations of patients of different ages and with no history of laryngeal cancer ...