We report here the integration of ring-opening metathesis polymerization (ROMP) and ring-opening polymerization of the amino acid N-carboxyanhydride (NCA) to allow facile synthesis of brush-like polymers containing polypeptide as the brush side chains. ROMP of N-trimethylsilyl norbornenes rendered the preparation of poly(norbornene)s bearing pendant N-TMS groups. With no need to purify the resu...

In this issue of Chem, Zhou and co-workers report a new strategy for synthesizing optically active N–C axially chiral compounds. the presence norbornene-ester-Pd catalyst, Catellani reaction iodobenzene derivatives with N-(2-substituted-phenyl)-2-bromobenzamides proceeds in highly enantioselective manner to give N-aryl-phenanthridinone derivatives. Atropisomeric biaryl C–C axis have been widely...

Well-defined molecular brushes bearing polypeptides as side chains were prepared by a "grafting through" synthetic strategy with two-dimensional control over the brush molecular architectures. By integrating N-carboxyanhydride ring-opening polymerizations (NCA ROPs) and ring-opening metathesis polymerizations (ROMPs), desirable segment lengths of polypeptide side chains and polynorbornene brush...

The morphology of a novel diblock copolymer, poly(norbornene methanol)-b-poly(norbornene dicarboxylic acid), was investigated before and after metal oxide doping by transmission electron microscopy (TEM) using a novel iodine vapor staining method to image the undoped polymer. A lamellar morphology was observed by TEM after staining the undoped diblock copolymer with iodine vapor. Thin film surf...

Nuclear magnetic resonance, broadband dielectric spectroscopy and dynamic-mechanical thermal analysis were employed to study molecular dynamics of ethylene-norbornene copolymer. The analysis of experimental data indicates existence of three motional processes denoted as α, β, and γ in order of decreasing temperature. The α relaxation is related to the dynamic glass transition, while the β relax...

Through a modular ROMP (ring-opening metathesis polymerization) strategy, a random copolymer with anti-thrombotic activity and imaging capability has been constructed from RGD, rhodamine B and PEG modified norbornene monomers. As we expected, these tri-component polynorbornenes exhibit significant enhancement in anti-thrombotic efficacy and bioavailability in vivo.

Aliphatic terminal alkenes react with pinacolborane at ambient temperature to afford dehydrogenative borylation compounds as the major product when iPr-Foxap is used as the ligand with cationic rhodium(I) in the presence of norbornene, which acts as the sacrificial hydrogen acceptor. The reaction is applied to the one-pot syntheses of aldehydes and homoallylic alcohols from aliphatic terminal a...

Based on (1)H NMR studies, subtle electronic factors rather than pre-organisation dictate the binding stoichiometry of the new, norbornene based, anion hosts 1 and 2 with acetate, however, the binding of dihydrogenphosphate appears to be based solely on steric constraints.

[{Mn(tmeda)}(3){GeSe(3)(OMe)}(2)] (), synthesized by the reaction of [K(4)(H(2)O)(3)][Ge(2)Se(6)] with MnCl(2).4H(2)O in MeOH-tmeda (tmeda = N,N,N',N'-tetramethyl-1,2-diaminoethane), exhibits an isosceles triangular arrangement of Mn(2+) ions that are antiferromagnetically coupled with an S = 3/2 ground state.