Tissue deformation in ultrasound (US) imaging leads to geometrical errors when measuring tissues due the pressure exerted by probes. Such has an even larger effect on 3D US volumes as correct compounding is limited inconsistent location and geometry. This work proposes a patient-specified stiffness-based method tissue deformations robotic acquisitions. To obtain model, palpation performed at sa...

Cyclosporin A (CyA) tissue distribution kinetics was extensively studied after single 1.2-, 6-, and 30-mg/kg CyA doses (via 2-min i.v. infusion) to rats. Drug concentrations in blood and various tissues were measured using a specific radioimmunoassay. Based on total blood concentration data alone, CyA systemic pharmacokinetics appeared essentially linear. However, after taking the saturable, no...

Tissue deformation in ultrasound imaging poses a challenge to the development of many image registration techniques, including multimodal image fusion, multi-angle compound image and freehand three-dimensional ultrasound. Although deformation correction methods are desired to provide images of uncompressed tissue structure, they have not been well-studied. A novel trajectory-based method to cor...