The current methods for treatment of cancers are inadequate and more specific methods such as gene therapy are in progress. Among different vehicles, cationic liposomes are frequently used for delivery of genetic material. This investigation aims to prepare and optimize DOTAP cationic liposomes containing an antisense oligonuclotide (AsODN) against protein kinase C alpha in non-small cells lung...

In all countries in the world as well Poland, there are no recommendations regarding testing of predictive factors qualifying non-small cell lung cancer (NSCLC) patients for molecularly targ...

Introduction: Little is known about long-term survivors after complete resection of non-small cell lung cancer. Therefore, this study clarified the characteristics 10-year-plus postoperative with recurrence.

Objective(s): Combination chemotherapy is a rational strategy to increase patient response and tolerability and to decrease adverse effects and drug resistance. Recently, the use of non-steroidal anti-inflammatory drugs (NSAIDs) has been reported to be associated with reduction in occurrence of a variety of cancers including lung cancer. On the other hand, growing evidences suggest that deuteri...

Ferroptosis therapy gradually becomes a new strategy for the treatment of non-small cell lung cancer (NSCLC) because its active iron metabolism. Because hypoxic microenvironment in NSCLC inhibits ferroptosis heavily,...

Comparison between the first-line and second-line immunotherapy drugs in progression-free survival overall advanced non-small cell lung cancer: a systematic review meta-analysis of randomized controlled trials

Background & objective: The histologic distinction of small cell from non-small cell lung carcinoma and correct identification of all subtypes of lung carcinoma are very important in treatment management. The main method for histologic classification of lung tumors is based on morphology. However, in small bronchoscopic biopsies in par...

-------------------------------------------------------------------ABSTRACT-------------------------------------------------------------Cancers is defined as the uncontrolled cell divisions. Cell does not grow maturely and destined to uncontrolled cell growth. When these cells of lungs grow uncontrolled it is called lung cancer. Nowadays mortality rate due to lung cancer is increasing day by da...