The treatment of migraine depends on the frequency, severity and concomitant diseases. There are several specific drugs developed for migraine prevention in addition to the additive antimigraine effects of some other non-specific drugs. The aim of this literature-based review is to summarize the possible antimigraine properties of different antihypertensive agents (beta-blockers, calcium channe...

BACKGROUND Relevant clinical studies have been small and have not convincingly demonstrated whether the perioperative initiation of beta-blockers should be considered in patients with diabetes mellitus undergoing noncardiac surgery. METHODS AND RESULTS In this nationwide propensity score-matched study, we included patients with diabetes mellitus undergoing noncardiac surgery between 2000 and ...

OBJECTIVES: To determine the prevalence and characteristics of patients who achieved target doses angiotensin converting enzyme inhibitors (ACEIs)/ II receptor blockers (ARBs), beta-blocker, mineralocorticoid antagonists (MRAs). MATERIALS AND METHODS: A retrospective chart review study heart failure with reduced ejection fraction (HFrEF) received ACEIs/ARBs, beta-blockers, or MRAs follow-up mor...

Although β1-blockers have been perioperatively used to reduce the cardiac disorders associated with general anesthesia, little is known about the mechanistic characteristics of ultra-short-acting highly selective β1-blocker landiolol. We studied its membrane-interacting property in comparison with other selective and non-selective β1-blockers. Biomimetic membranes prepared with phospholipids an...

Abstract Background The combination of endoscopic band ligation and beta-blockers is the standard care treatment for secondary prevention variceal bleeding; however, rebleeding still occurs with associated high mortality. Simvastatin (a lipid-lowering agent) was found to reduce portal hypertension decrease hepatic fibrosis. This study aimed assess effect adding simvastatin therapy prevent its i...

BACKGROUND AND AIMS Previous clinical trials suggest that adding non-selective beta-blockers improves the efficacy of endoscopic band ligation (EBL) in the prevention of recurrent bleeding, but no study has evaluated whether EBL improves the efficacy of beta-blockers + isosorbide-5-mononitrate. The present study was aimed at evaluating this issue in a multicentre randomised controlled trial (RC...

Involuntary movement disorders include tremors, tics, myoclonus, athetosis, chorea, dystonia, and dyskinesia. Neuroleptic drugs have the propensity to cause extrapyramidal side effects. Lithium-induced coarse tremors are well documented may occur at therapeutic serum concentrations (0.8-1.0 mEq/L) in treatment of bipolar disorder. Treatment for due lithium includes either dose reduction or non-...