BACKGROUND Bael (Aegle marmelos (L.) Corr.) has been widely used in indigenous systems of Indian medicine to exploit its medicinal properties including astringent, antidiarrheal, antidysenteric, demulcent, antipyretic, antiulcer, anti-inflammatory and anti cancer activities. The present study aims to evaluate the antioxidative and antiulcer effect of methanolic extract of unripe fruit of Aegle ...

Present study focuses on the evaluation of butyl p-hydroxybenzoic acid (butylparaben CAS No: 94-26-8) exerted hepatotoxicity in mice. Oral administration of three different doses of butylparaben (40, 20 and 13.33 mg/0.2 mL olive oil/kg b.w./day) for 30 days has resulted in marked increase in lipid peroxidation. The effect was dose-dependent. Biochemical analysis revealed significant (p < 0.05) ...

In this study, the activity of methanol extract of Prosopis cineraria (MPC) was evaluated in N-nitrosodiethylamine (DEN, 200mg/kg) induced experimental liver tumor in male Wistar rats. It was found that the administration of MPC (200 and 400mg/kg) effectively suppressed liver tumor induced by N-nitrosodiethylamine (DEN) as revealed by decrease in N-nitrosodiethylamine (DEN) induced elevated lev...

OBJECTIVES The present study was an attempt at investigating whether the aqueous extract of Emblica officinalis may have an ameliorative effect on ochratoxin-induced lipid peroxidation in the kidney and liver of mice. METHODS Adult male albino mice were orally administered 50 microg (LD, low dose) and 100 microg (HD, high dose) of ochratoxin/0.2 ml of olive oil/animal/day for 45 days. RESUL...

Hepatoprotective activity of hydroalcoholic extract of Luffa acutangula (HAELA) against carbon tetrachloride (CCl4) and rifampicin-induced hepatotoxicity in rats was evaluated and probable mechanism(s) of action has been suggested. Administration of standard drug- silymarin and HAELA showed significant hepatoprotection against CCl4 and rifampicin induced hepatotoxicity in rats. Hepatoprotective...

Over-production of reactive oxygen species (ROS) in plants under stress conditions is a common phenomenon. Plants tend to counter this problem through their ability to synthesize ROS neutralizing substances including non-enzymatic and enzymatic antioxidants. In this context, ascorbic acid (AsA) is one of the universal non-enzymatic antioxidants having substantial potential of not only scavengin...