Postsynthetic covalent modification of metal-organic frameworks (MOFs) with long alkyl substituents is shown to protect these materials against moisture. These MOFs, which normally display hydrophilic properties, are readily converted into hydrophobic or superhydrophobic materials. Overcoming the inherent sensitivity of MOFs to water represents a major step forward in their widespread use in te...

This article describes an integrated rate equation for the time course of covalent enzyme inhibition under the conditions where the substrate concentration is significantly lower than the corresponding Michaelis constant, for example, in the Omnia assays of epidermal growth factor receptor (EGFR) kinase. The newly described method is applicable to experimental conditions where the enzyme concen...

The review is stanch to supramolecular chemistry and theirvaious molecular assemblies. It mainly deals with applications of calix system, non-covalent interaction, fluorescence sensor, biosensor, nano biosensor. Recognition many moieties via suitable attached groups captivates the attention In addition it also highly selective specific towards bio molecules, anions, cations neutral substrate.

By drawing on nature conceptually, the practice of chemical synthesis can now be broadened in scope to include the supramolecular synthesis of supermolecules and their postassembly covalent modification to form mechanically interlocked molecules, which the chemist can use to build functioning nanosystems after the style of those found in the living world.

Investigations into the photocrosslinking kinetics of the protein Tus with various bromodeoxyuridine-substituted Ter DNA variants highlight the potential use of this complex as a photoactivatable connector between proteins of interest and specific DNA sequences.

A microscopic empirical model of bulk modulus based on atomic-scale parameters is proposed. These parameters include the bond length, the effective bonded valence electron (EBVE) number, and the coordination number product of two bonded atoms, etc. The estimated bulk moduli from our model are in good agreement with experimental values for various polar covalent crystals including ionic crystals...

The synthesis of one-dimensional tubular polymers via a preorganization-polymerization approach is presented. Prior to polymerization, photo-reactive monomers self-assemble into one-dimensional tubular structures in aqueous medium. The supramolecular polymers are subsequently converted into covalent polymers by light-induced anthracene dimerization.

A set of recombinant artificial proteins that can be cross-linked, by either covalent bonds or association of helical domains or both, is described. The designed proteins can be used to construct molecular networks in which the mechanism of crosslinking determines the time-dependent responses to mechanical deformation.

We describe the facile synthesis of several two-dimensional covalent-organic frameworks (2D COFs) as films by vapor-assisted conversion at room temperature. High-quality films of benzodithiophene-containing BDT-COF and COF-5 with tunable thickness were synthesized under different conditions on various substrates. BDT-COF films of several micrometer thickness exhibit mesoporosity as well as text...