The aim of this study was to describe the use of thalidomide in the treatment of prurigo nodularis Hyde (PNH) refractory to other treatments or in cases where other treatments cannot be used due to side effects. 77 medical records were retrospectively reviewed for the following data: sex, age, age at the beginning of thalidomide treatment, dermatological diagnosis, duration of the skin disease,...

© 2011 The Authors. doi: 10.2340/00015555-0997 Journal Compilation © 2011 Acta Dermato-Venereologica. ISSN 0001-5555 Prurigo nodularis (PN) is a chronic and intensely pruritic dermatosis characterized by lichenified and excoriated papules and nodules. Although thalidomide has shown promise in the treatment of refractory PN, its safety and efficacy for this indication has not been firmly establi...

nodular fasciitis of the breast is a rare benign pathology of soft tissue that is a consequence of fibroblastic hyperplasia within breast. it can mimic breast cancer clinically, radiologically, and histopathologically. a-43 year-old female with a painless mass within upper-lateral quadrant of her left breast complained of rapid and progressive growth during previous few days. no evidence of nip...

castleman's disease is an uncommon cause of lymph node enlargement that mostly involves the mediastinum and lung hilum. it is divided into 2 types: localized, which is usually asymptomatic and presents with a mass lesion; and multicentric, which is characterized by chills, anemia, generalized lymphadenopathy and hepatosplenomegaly. an extrathoracic site of involvement is very uncommon, and may ...

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Until recently the specific dermatoses of pregnancy were ill-understood and characterized by numerous and rather misleading terminology. In 19831 the following simplified clinical classification of the specific dermatoses of pregnancy was proposed: 1) Pemphigoid "Herpes" Gestationis. 2) Polymorphic Eruption of Pregnancy (PUPPP). 3) Prurigo of Pregnancy (papular dermatitis). 4) Pruritic Follicul...