We analysed testicular samples of NMRI mice every 2 h of a day in order to determine whether there is a circadian rhythm in spermatogenetic activity. We used flow cytometry after staining the DNA with DAPI. The highest proportion of DNA synthesizing cells (mainly spermatogonia and preleptotene spermatocytes) was seen at 8 p.m. and especially at 10 p.m.; the lowest proportion was observed at 2 p...

The intermediate-filament proteins in Sarcoma 180 ascites cells and solid tumors generated by s.c. injection of ascites cells in NMRI or nude mice were analyzed by one- and two-dimensional gel electrophoresis and identified by immunological methods. The ascites form of Sarcoma 180 coexpresses keratin and vimentin, whereas the solid tumor ceases to synthesize keratins but continues to express vi...

Biological effects of piroxicam, metamizol, and S-adenosylmethionine (S-AMET) have been tested in NMRI mice infected intraperitoneally with Trichomonas vaginalis. An intraperitoneal treatment during ten preinfection days with piroxicam (10 mg/Kg/day), or metamizol (275 mg/Kg/day), but not with S-AMET (117 mg/Kg/day) induced a significant decrease of abdominal lesions and mortality, assessed by ...

Neutrophils are the key players in inflammatory reactions and the release of superoxide through the NADPH-oxidase upon neutrophil activation contributes to bacterial clearance and surrounding tissue damage. Here we describe data on the mouse neutrophil NADPH-oxidase activation induced by the mouse formyl peptide receptor (Fpr) agonist WKYMVm and galectin-3. Neutrophils isolated from bone marrow...

Application of nuclear magnetic resonance imaging (NMRI) as a non-invasive and accurate imaging procedure has been widely used in recent years. Meanwhile, the biological effects of magnetic fields of several tesla (T) and high energy radiofrequency (RF) is not fully known yet. Because of controversy over this issue, the present research has been carried out in order to verify the effects of...

Background: The quality and quantity of the diet has undeniable effects on the reproduction of organisms. We examined the effects of two diets (with and without mineral supplementation-Vitamins) on super-ovulation in two strains of mice (B6D2F1 and NMRI) in Royan Institute, Tehran. Materials and Methods: For this purpose, 40 female mice (21 days) from each strain were divided into four experime...