background: acute opioid overdose is a common cause of admission in emergency department. in spite of the fact that naloxone is the main therapy for decades, there are controversies about the proper way of its use. this study aimed to compare two most recommended administration modes for naloxone. methods: in this single-blind clinical trial, 80 patients with methadone overdose syndrome were ra...

background: intoxication with aluminum phosphide has been prevalent in iran recently. lab confirmation of the poisoning is needed in clinical and post-mortem settings. present study was conducted to determine efficiency and validity of silver nitrate test for detection of aluminum phosphide in samples. methods: information about dead patients with history of aluminum phosphide poisoning referre...

how to cite this article: fayyazi a, khajeh a, bagheri m, ahmadi s. acute hydrocephaly following methadone intoxication in a child. iranian journal of childneurology 2012;6(1):35-38. infantile methadone intoxication has been on the rise since the usage of methadone in opioid detoxification programs. we report a 30-month-old child with encephalopathy and acute hydrocephaly following methadone in...

Introduction A subset of frequent users of emergency services are those who use the emergency department (ED) for acute alcohol intoxication. This population and their ED encounters have not been previously described. Methods This was a retrospective, observational, cohort study of patients presenting to the ED for acute alcohol intoxication between 2012 and 2016. We collected all data from t...

Nitrate and nitrite concentrations in the water and nitrous oxide and nitrite fluxes across the sediment-water interface were measured monthly in the River Colne estuary, England, from December 1996 to March 1998. Water column concentrations of N(2)O in the Colne were supersaturated with respect to air, indicating that the estuary was a source of N(2)O for the atmosphere. At the freshwater end ...

Nitrite is a storage reservoir of nitric oxide that is readily reduced to nitric oxide under pathological conditions. Previous studies have demonstrated that nitrite levels are significantly reduced in cardiovascular disease states, including peripheral vascular disease. We investigated the cytoprotective and proangiogenic actions of a novel, sustained-release formulation of nitrite (SR-nitrite...

narK mutants of Escherichia coli produce wild-type levels of nitrate reductase but, unlike the wild-type strain, do not accumulate nitrite when grown anaerobically on a glucose-nitrate medium. Comparison of the rates of nitrate and nitrite metabolism in cultures growing anaerobically on glucose-nitrate medium revealed that a narK mutant reduced nitrate at a rate only slightly slower than that i...

ABSTRACT Background: Aluminum phosphide as a fumigant is extensively used for wheat preservation from rodents and bugs especially in silos worldwide. There is increasing number of acute intoxication with this potentially lethal compound because of its easy availability. We have tried to locate predictors of poor prognosis in patients with aluminum phosphide intoxication in order to find patien...

GHB intoxication must be considered in children with coma and a suspicion of drug intoxication. Furthermore, mixed intoxication with several substances and the possibility of unpredictable symptom profiles should be anticipated to ensure optimal symptomatic treatment of patients.

PURPOSE Gait impairment due to encephalopathy and neuropathy has been reported in carbon monoxide (CO) intoxication. Heterotopic ossification (HO) as a cause of gait impairment after CO intoxication has never been reported. In this study we report a patient with HO after CO intoxication. CASE REPORT A 21 year-old woman developed HO after CO intoxication, which resulted in progressive difficul...