Abstract Background Non-invasive prenatal screening (NIPS) is widely used as the alternative choice for pregnant women at high-risk of fetal aneuploidy. However, whether NIPS has a good detective efficiency advanced maternal age (AMA) not been fully studied especially in Chinese women. Methods Twenty-nine thousand three hundred forty-three AMA with singleton pregnancy who received and followed-...

In the current paradigm for molecular imprinting, the imprinted binding sites exist as a consequence of the polymerization process around templates, and the properties of nonimprinted polymers (NIPs) have largely been overlooked. Thus, nothing can be affirmed a priori concerning the binding properties of NIPs. We propose an alternative view where the imprinting effect is due to the presence of ...

Neural Information Processing Systems (NIPS) is a top-tier annual conference in machine learning. The 2016 edition of the conference comprised more than 2,400 paper submissions, 3,000 reviewers, and 8,000 attendees, representing a growth of nearly 40% in terms of submissions, 96% in terms of reviewers, and over 100% in terms of attendees as compared to the previous year. In this report, we anal...

In this paper we define Clinical Data Intelligence as the analysis of data generated in the clinical routine with the goal of improving patient care. We define a science of a Clinical Data Intelligence as a data analysis that permits the derivation of scientific, i.e., generalizable and reliable results. We argue that a science of a Clinical Data Intelligence is sensible in the context of a Big...

1. Laboratory of Molecular Biophysics, Department of Cell and Molecular Biology, Uppsala University, Husargatan 3 (Box 596), SE-75124 Uppsala, Sweden 2. National Institute for Physiological Sciences (NIPS), Okazaki, Aichi, 444-8585 Japan 3. Structural and Genomic Information Laboratory, UMR 7256 (IMM FR 3479) Centre National de la Recherche Scientifique & Aix-Marseille University, Marseille, 13...

Major intrinsic proteins (MIPs) family include the group of also called channel or water channels. Aquaporins facilitate transport and other uncharged small molecules, forming pores in cellular boundaries which help plant growth, development, sometimes adaptation. They usually have six tranSmembrane alpha-helical domains with conserved amino acids residues along hydrophobic hydrophilic regions....

Aqueous phase separation (APS) is a recently developed sustainable alternative to the conventional organic solvent based nonsolvent-induced (NIPS) method prepare polymeric membranes. In APS, polyelectrolytes are precipitated from aqueous solutions through pH or salinity switches. Although APS differs NIPS in polymer and solvents, they share many tuning parameters. this work, we investigate APS-...

Redox flow batteries (RFBs) are emerging as viable options for grid-scale energy storage, but their elevated costs hamper commercialization. Enhancing the porous carbon electrode performance to improve power density and reduce system is an effective strategy toward widespread deployment; however, must satisfy multiple contradictory roles, including providing high surface area, low pressure drop...

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