Niosomes are non-ionic surfactant vesicles inclosing an aqueous phase and a wide range of molecules could be encapsulated within aqueous spaces of lipid membrane vesicles. They are microscopic lamellar structures formed on the admixture of a non-ionic surfactant, cholesterol and phosphate with subsequent hydration in aqueous media. Niosomes belongs to novel drug delivery system which offers a l...

Niosomes are non-ionic surfactant vesicles obtained on hydration of synthetic nonionic surfactants, with or without incorporation of cholesterol or other lipids. They are vesicular systems similar to liposomes that can be used as carriers of amphiphilic and lipophilic drugs. Niosomes are promising vehicle for drug delivery and being non-ionic, it is less toxic and improves the therapeutic index...

Niosomes have potential applications in topical drug delivery system. play an increasingly important role as they can reduce toxicity and modify pharmacokinetic bio-availability. Topically applied niosomes increase the residence time of drugs stratum corneum epidermis, while reducing systemic absorption drug. It act containing reservoirs modification vesicular compositions or surface properties...