The title complex, [Ni(2)(C(42)H(46)Cl(2)N(6)O(2))(C(2)H(3)O(2))]ClO(4)·2CH(3)CN, was synthesized by condensation of 2,6-diformyl-4-chloro-phenol with N,N-bis-(amino-prop-yl)benzyl-amine in the presence of Ni(II) ions. The ligand is a 28-membered macrocycle with two identical pendant arms. The coordination geometries of the Ni atoms are both octa-hedral. The two Ni atoms are bridged by two phen...

The title dinuclear nickel(II) complex, [Ni(2)Cl(4)(C(11)H(10)N(2)O)(2)], lies on a centre of symmetry located at the centroid of the four-membered ring formed by the two Ni atoms and the bridging chloride ions. The Ni(II) atom is five-coordinated in a square-pyramidal geometry by the imine and pyridine N atoms of the Schiff base ligand, and by one terminal and two bridging Cl atoms. The Ni⋯Ni ...

Rhizobitoxine produced by Bradyrhizobium species strongly prevented derepression of hydrogenase expression in free-living Bradyrhizobium japonicum, although the toxin had no effect on the activity of cells which had already synthesized hydrogenase protein. Dihydrorhizobitoxine, a structural analog of rhizobitoxine, proved to be a less potent inhibitor of hydrogenase derepression. Rhizobitoxine ...

The iron-sulfur-cluster-free hydrogenase Hmd (H(2)-forming methylenetetrahydromethanopterin dehydrogenase) from methanogenic archaea has recently been found to contain one iron associated tightly with an extractable cofactor of yet unknown structure. We report here that Hmd contains intrinsic CO bound to the Fe. Chemical analysis of Hmd revealed the presence of 2.4 +/- 0.2 mol of CO/mol of iron...

Lipid-based nanoparticles (NPs) with a small amount of surface-chelated nickel (Ni-NPs) were developed to easily formulate the HIV his-tagged Tat protein, as well as to formulate and co-deliver two HIV antigens (his-p24 and his-Nef) on one particle. Female BALB/c mice were immunized by s.c. injection with his-Tat/Ni-NP formulation (1.5 μg Tat-his/mouse) and control formulations on day 0 and 14....

This article presents a set of low-temperature deposition and etching processes for the integration of electrochemically deposited Ni-Fe alloys in complex magnetic microelectromechanical systems, as Ni-Fe is known to suffer from detrimental stress development when subjected to excessive thermal loads. A selective etch process is reported which enables the copper seed layer used for electrodepos...

Paramagnetic [Ni('NMeS4')]2 1 ('N MeS4'2_ = 2.2'-Bis(2-mercaptophenylthio)diethylmethylam in e(2-)) was synthesized from N i(ac)2 and Na2-'N MeS4' and characterized by X-ray structure analysis. In solid state, 1 contains two pseudo-octahedral [N i('N MeS4')] fragments bridged via thiolate donors. In contrast to the parent complex [N i('N HS4')]2, the thiolate and thioether donors coordinate cis...

In the title salt-type 1:2 adduct, [Ni(C(16)H(36)N(4))](C(14)H(14)O(2)PS(2))(2) or [Ni(tet-a)][S(2)P(OCH(2)Ph)(2)](2), where tet-a is meso-5,5,7,12,12,14-hexa-methyl-1,4,8,11-tetra-azacyclo-tetra-decane, the [Ni(tet-a)](2+) complex cation exhibits a relatively undistorted square-planar geometry about the Ni atom, which lies on an inversion centre and is coordinated by four macrocyclic N atoms. ...

Glutathione, Upsilon-Glu-Cys-Gly, is one of the most abundant small molecules in biosphere. Its main form is the reduced monomer (GSH), serving to detoxicate xenobiotics and heavy metals, reduce protein thiols, maintain cellular membranes and deactivate free radicals. Its oxidized dimer (GSSG) controls metal content of metallothionein. The results presented provided a quantitative and structura...

The title compound, [Ni(C(2)H(8)N(2))(C(6)H(18)N(4))]S(2)O(3)·3H(2)O, was accidentally synthesized under solvothermal conditions applying [Ni(en)(3)]Cl(2) (en is ethane-1,2-diamine) as the Ni source. The asymmetric unit consists of one discrete [Ni(tren)(en)](2+) complex [tren is N,N-bis-(2-amino-eth-yl)ethane-1,2-diamine] in which the Ni(2+) cation is sixfold coord-inated within a slightly dis...