نتایج جستجو برای: ngs

تعداد نتایج: 5131  

2017

Next-generation sequencing (NGS) technologies including DNA sequencing and RNA sequencing provide “omics” approaches to reveal genomic, transcriptomic, and epigenomic landscapes of individual cancers. A variety of genomic aberrations can be screened simultaneously, such as common and rare variants, structural variations (e.g. insertions and deletions), copy-number variation, and fusion transcri...

Journal: :Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 2014
V P Retèl S E Joosten W H van Harten

PCN215 Next GeNeratioN SequeNCiNG teChNoloGy: health teChNoloGy aSSeSSmeNt, market aCCeSS treNdS aNd PoteNtial imPaCtS oN the Future oF ComPaNioN diaGNoStiC teStiNG Faulkner E.C.1, Spinner D.S.2, Ransom J.F.3, Paul A.4, Chawla A.S.5, Doyle J.J.6, Shaw W.H.2, Fitzgerald J.T.2 1Institute for Pharmacogenomics and Individualized Therapy, Eshelman School of Pharmacy, University of North Carolina, Ch...

2014
Yueqiu Tan Xuyang Yin Shuoping Zhang Hui Jiang Ke Tan Jian Li Bo Xiong Fei Gong Chunlei Zhang Xiaoyu Pan Fang Chen Shengpei Chen Chun Gong Changfu Lu Keli Luo Yifan Gu Xiuqing Zhang Wei Wang Xun Xu Gábor Vajta Lars Bolund Huanming Yang Guangxiu Lu Yutao Du Ge Lin

BACKGROUND Next generation sequencing (NGS) is now being used for detecting chromosomal abnormalities in blastocyst trophectoderm (TE) cells from in vitro fertilized embryos. However, few data are available regarding the clinical outcome, which provides vital reference for further application of the methodology. Here, we present a clinical evaluation of NGS-based preimplantation genetic diagnos...

2017
Christoph Endrullat

2 generation sequencing or better known as next-generation sequencing (NGS) represents a cutting-edge technology in life sciences and current foundation for unravelling nucleotide sequences. Since advent of first platforms in 2005 the number of different types of NGS platforms increased in the last 10 years in the same manner as the variety of possible applications. Higher throughput, lower cos...

پایان نامه :دانشگاه آزاد اسلامی - دانشگاه آزاد اسلامی واحد تهران مرکزی - دانشکده علوم 1390

حفاری سازندهای شیلی به دلیل ویژگیهای خاص آنها با مشکلات متعددی نظیر ریزش دیواره، گیر کردن مته و حتی از دست دادن چاه همراه است که ارائه هر نوع راهکاری برای رفع این مشکل، نیازمند شناخت لیتولوژی این سازندها و کانی های رسی موجود درآنهاست. از این رو کانی های رسی سازندهای پابده و گورپی که از جمله سازندهای مشکل ساز در حفاری میادین نفتی می باشند، به کمک نمودار الکتریکی ngs مورد بررسی قرار گرفت . همچنین...

Journal: : 2021

This review presents basic principles and methods of next-generation sequencing (NGS) discusses a number the latest papers on possibilities, stages NGS, as well application NGS in medical research, particularly, clinical microbiology infectious diseases, epidemiology. The development technologies will allow improving results diagnostics, treatment prevention diseases opens up new prospects for ...

Journal: :Journal of computational biology : a journal of computational molecular cell biology 2012
Zhiyuan Zhai Gesine Reinert Kai Song Michael S. Waterman Yihui Luan Fengzhu Sun

Next generation sequencing (NGS) technologies are now widely used in many biological studies. In NGS, sequence reads are randomly sampled from the genome sequence of interest. Most computational approaches for NGS data first map the reads to the genome and then analyze the data based on the mapped reads. Since many organisms have unknown genome sequences and many reads cannot be uniquely mapped...

2015
Manonanthini Thangam Ramesh Kumar Gopal

Next generation sequencing (NGS) innovations put a compelling landmark in life science and changed the direction of research in clinical oncology with its productivity to diagnose and treat cancer. The aim of our portal comprehensive resources for cancer NGS data analysis (CRCDA) is to provide a collection of different NGS tools and pipelines under diverse classes with cancer pathways and datab...

2013
Darragh G. McArt Philip D. Dunne Jaine K. Blayney Manuel Salto-Tellez Sandra Van Schaeybroeck Peter W. Hamilton Shu-Dong Zhang

The advent of next generation sequencing technologies (NGS) has expanded the area of genomic research, offering high coverage and increased sensitivity over older microarray platforms. Although the current cost of next generation sequencing is still exceeding that of microarray approaches, the rapid advances in NGS will likely make it the platform of choice for future research in differential g...

2017
Wycliff M. Kinoti Fiona E. Constable Narelle Nancarrow Kim M. Plummer Brendan Rodoni

The distribution of Ilarvirus species populations amongst 61 Australian Prunus trees was determined by next generation sequencing (NGS) of amplicons generated using a genus-based generic RT-PCR targeting a conserved region of the Ilarvirus RNA2 component that encodes the RNA dependent RNA polymerase (RdRp) gene. Presence of Ilarvirus sequences in each positive sample was further validated by Sa...

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