NeM: nevoid melanoma RCM: reflectance confocal microcopy INTRODUCTION Nevoid melanoma (NeM) is an uncommon subtype of melanoma that can mimic the morphology of an intradermal nevus both clinically and histopathologically. Similar to other melanoma subtypes, NeM is prone to local recurrence and metastasis, necessitating early diagnosis and prompt management. Recently, reflectance confocal microc...

GoRLiN, R. J., VICKERS, R. A., KELLN, E., and WILLIAMSON, J. J., 'Multiple basal-cell nevi syndrome. An analysis of a syndrome consisting of multiple nevoid basal-celled carcinoma, jaw cysts, skeletal anomalies, medulloblastoma, and hyporesponsiveness to parathormone', Cancer, 1965, 18, 89. HOWELL, J. B., ANDERSON, D. E., and MCCLENDON, J. L., 'The basal cell nevus syndrome', J. Am. med. Ass., ...

The human homologue of the Drosophila segment polarity gene patched (PTCH) has recently been identified as the tumor suppressor gene responsible for the nevoid basal cell carcinoma (BCC) syndrome (H. Hahn et al., Cell, 85: 841-851, 1996; R. L. Johnson et al., Science (Washington DC), 272: 1668-1671, 1996). In addition to multiple BCCs, patients with nevoid BCC syndrome have a predisposition for...