PURPOSE To report the use of corneal collagen crosslinking in the treatment of infective keratitis not responding to antimicrobial therapy. METHODS Two retrospective case reports of infective keratitis treated with corneal collagen crosslinking. RESULTS In both cases, corneal collagen crosslinking caused a rapid resolution of the infective keratitis, leaving residual stromal scarring. Due t...

Background & Aims: Exposure Keratitis (EK) is a common problem in critically ill patients admitted to the Intensive Care Unit (ICU). We conducted exposure keratitis in mechanical ventilatory patients in the intensive care unit of Imam Khomeini Hospital in Urmia for five years. Materials & Methods: In this retrospective cross-sectional study, the records of the patients were taken from the medi...

BACKGROUND Fungal keratitis is an important cause of corneal blindness all over the world. Although there are several reports on fungal keratitis from developing and developed countries, fungal keratitis in Ethiopia is poorly known. The aim of this study was to determine the prevalence of fungal keratitis and spectrum of fungi implicated in causing the infection. METHODS The present study was...

Pubmed and Medline were searched for articles referring to Pseudomonas keratitis between the years 2007 and 2012 to obtain an overview of the current state of this disease. Keyword searches used the terms "Pseudomonas" + "Keratitis" limit to "2007-2012", and ["Ulcerative" or "Microbial"] + "Keratitis" + "Contact lenses" limit to "2007-2012". These articles were then reviewed for information on ...

Purpose. To review the newer treatments for bacterial keratitis. Data Sources. PubMed literature search up to April 2012. Study Selection. Key words used for literature search: "infectious keratitis", "microbial keratitis", "infective keratitis", "new treatments for infectious keratitis", "fourth generation fluoroquinolones", "moxifloxacin", "gatifloxacin", "collagen cross-linking", and "photod...

AIM To study herpes simplex virus (HSV) DNA in tears from patients with atypical epithelial keratitis of unknown aetiology. METHODS Tear samples were collected from 17 affected eyes of 17 consecutive patients suffering from epithelial keratitis in whom HSV keratitis was suspected but whose diagnosis was difficult on the basis of clinical manifestations alone. Using reduced sensitivity polymer...

Infections of the cornea can lead to corneal opacity and blindness if not identified quickly and managed appropriately. The terms ‘microbial keratitis’, ‘infective keratitis’ and ‘suppurative keratitis’ are all used to describe suppurative infections of the cornea. In this issue we use the term microbial keratitis. These infections are characterised by the presence of white or yellowish infiltr...

Infections of the cornea can lead to corneal opacity and blindness if not identified quickly and managed appropriately. The terms ‘microbial keratitis’, ‘infective keratitis’ and ‘suppurative keratitis’ are all used to describe suppurative infections of the cornea. In this issue we use the term microbial keratitis. These infections are characterised by the presence of white or yellowish infiltr...

Pseudomonas aeruginosa and Staphylococcus aureus are the two dominant Gram-negative -positive species, respectively, isolated from patients with contact lens-related bacterial keratitis. The clinical features of keratitis vary, such that timely differential diagnosis can be challenging, which may cause a delay in resulting poorer outcome. This review aims to explore current understanding immuno...

Microbial keratitis is a major cause of corneal opacity and loss of vision worldwide. Ulcerative microbial keratitis remains a leading cause of blindness worldwide. The most common causative organisms are bacteria, although fungi and protists can also cause keratitis. Bacterial keratitis is potentially more devastating ocular infection. The most common bacteria associated with corneal ulcer are...