نتایج جستجو برای: neurological injury
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BACKGROUND Tailored craniotomies for awake procedures limit cortical exposure. Recently we demonstrated that the identification of eloquent areas increased the risk of postoperative deficits. However, it was not clear whether the observed neurological deficits were caused by proximity of functional cortex to the tumor [cortical injury] or subcortical injury. OBJECTIVE We hypothesize that subc...
objective(s) clinical studies of treating traumatic brain injury (tbi) with autologous adult stem cells led us to examine the impression of a combination therapy. this was performed by intravenous injection of human umbilical cord matrix stem cell (hucmsc-wharton,s jelly stem cell) with bone marrow cell mobilized by granulocytecolony stimulating factor (g-csf) in rats injured with cortical comp...
Traumatic Brain Injury (TBI) was chosen as an Emergency Neurological Life Support topic due to its frequency, the impact of early intervention on outcomes for patients with TBI, and the need for an organized approach to the care of such patients within the emergency setting. This protocol was designed to enumerate the practice steps that should be considered within the first critical hour of ne...
Trauma is the leading cause of death and long term disablement in young persons. Head injury accounts for about 30% of traumatic deaths and a higher proportion of long term disablement. Historically the emphasis of reviews on head injury has concentrated on the acute phase of treatment and has thus adopted a neurosurgical perspective. As a result, much of the content is peripheral to neurologic...
The hallmark of concussion injuries of the nervous system is the rapid and complete resolution of neurological deficits. Cerebral concussion has been well studied, both clinically and experimentally. In comparison, spinal cord concussion (SCC) is poorly understood. The clinical and radiological features of 19 SCC injuries in the general population are presented. Spinal cord injuries were classi...
Traumatic brain injury is not a discrete event but an unfolding sequence of damage to the central nervous system. Not only the acute phase but also the subacute and chronic period after injury, i.e., during inpatient rehabilitation, is characterized by multiple neurotransmitter alterations, cellular dysfunction, and medical complications causing additional secondary injury. Neuroendocrine distu...
Trauma to skull base or sinus is the most common cause of pneumocephalus. There are only few published reports of traumatic pneumocephalus secondary to penetrating injury of upper spine, epidural anaesthesia and lumber puncture. Till date only one case of pneumocephalus and pneumorrhachiasis after thoracic spine stab injury is reported in available English literature that too associated without...
Studies with omega-3 polyunsaturated fatty acids (PUFA) have shown that these compounds have therapeutic potential in several indications in neurology and psychiatry. Acute spinal cord injury (SCI) is an event with devastating consequences, and no satisfactory treatment is available at present. The pathogenetic mechanisms associated with SCI include excitotoxicity, increased oxidation and infla...
The therapeutic efficacy of stem cell therapy in many diseased organs based greatly on their paracrine effect. neural cells are thought to have a role improving the neurological functional, recovery, and reduction cerebral infarction caused by ischemia/ reperfusion [I/R] injury rats.
Fetal cortical tissue was injected into injured adult rat brains following concussive fluid percussion (FP) brain injury. Rats subjected to moderate FP injury received E16 cortex transplant injections into lesioned motor cortex 2 days, 1 week, 2 weeks, and 4 weeks post injury. Histological assessment of transplant survival and integration was based upon Nissl staining, glial fibrillary acidic p...
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