Gastric neuroendocrine carcinomas are rare and have a poor prognosis, and the diagnostic criteria for this disease have recently changed. We herein report a case of sporadic gastric neuroendocrine carcinoma. A 75-year-old man was referred to our hospital with epigastric pain. Endoscopic examination revealed a localized ulcerative lesion (diameter, 4 cm) at the upper stomach. The diagnosis on bi...

Neuroendocrine tumor of the breast is a rare tumor that is under diagnosed and treated. This is a retrospective study over three years of neuroendocrine breast carcinoma cases seen at the National Institute of Oncology in Morocco between May 2007 and 2010. We analyzed various characteristics: Patient demographics, histological diagnosis, disease stage, treatment effects and outcome, in 7 non-me...

This paper discusses a rare case of small cell neuroendocrine carcinoma of the larynx. The diagnosis was based on histological investigation expanded with immunohistochemical tests of a fragment of a tissue taken through laryngofissure. The treatment in case of small cell carcinoma diagnosis differs from the treatment in case of other neuroendocrine carcinomas and squamous cell carcinomas of th...

We report a new case of Primary hepatic neuroendocrine carcinoma admitted in our hospital and revealed in 53 years man by epigastric pain and flush syndrome. A liver biopsy with immunohistochemical study confirmed the original location of a neuroendocrine carcinoma. After 12 cures of Chemotherapy and a follow up of 12 months, the patient is still in complete remission.

Neuroendocrine neoplasms are defined as epithelial neoplasms with predominant neuroendocrine differentiation. They can arise in almost every organ of the body although they are most commonly found in the gastrointestinal tract and respiratory system. Nasal cavity and paranasal sinuses are a rare site for neuroendocrine carcinoma. In contrast to the other regions, neuroendocrine tumours of the s...

Small cell neuroendocrine carcinoma of the paranasal sinuses was first described by Raychowdhuri in 1965 [10], drawing attention to the resemblance between the lesion and pulmonary small cell carcinoma. We report a case of small cell neuroendocrine carcinoma of ethmoid sinus with invasion of the upper medial aspect of right maxillary sinus and medial aspect of right orbit. The optimal treatment...

This is a new case of Merkel cell carcinoma of the vulva. It is a rare neuroendocrine carcinoma with an aggressive behavior. Because of its rarity in this location, it is not clear whether it behaves differently from the usual neuroendocrine carcinomas of the skin. A case of a 63-year-old patient with vulvar Merkel carcinoma is presented. The clinical presentation, microscopic and immunohistoch...

Objective: To analyze and compare clinico-pathologic characteristics and survival between lung tumors with mixed histologic pattern and our population of resected lung tumors with single histology in the same period. Methods: From January 1993 to December 1999, 1158 patients received resection for lung tumors. Of these, 59 (5.1%) presented a mixed histologic pattern on the surgical specimen. Th...

Neuroendocrine carcinomas are rare tumors. In the head and neck region they are most common in the larynx, where they represent 0.5-1% of epithelial cancers. Diagnosis requires the recognition of the typical neuroendocrine architecture and morphology and the immunohistochemical confirmation of neuroendocrine differentiation. In the 1991 WHO classification laryngeal neuroendocrine carcinomas hav...

Lynch syndrome (LS) is a common hereditary caused by mutations in deoxyribonucleic acid mismatch repair genes, with high probability of gastrointestinal, gynaecological and other cancers. The most LS-associated gastric cancer adenocarcinoma the intestinal type. Neuroendocrine neoplasia has not been well understood cancer. Herein, we report case 68-year-old female, history ascending colon seven ...