نتایج جستجو برای: neural stemprogenitor cells
تعداد نتایج: 1650920 فیلتر نتایج به سال:
Adult neurogenesis, a concept emergent in the late 1990s, is the generation of new neurons in the adult brain. This process occurs thank to cells who have this proliferative feature, named as Neural Stem Cells (NSCs). Neural Stem Cells (NSCs) are primary progenitors who can generate the two neural types (neurons and glia). Classically it was assumed that NSCs are only present in the embryo, but...
objective: mesenchymal stem cells (mscs) can differentiate into various cell types. since cysteine has structural similarities to neuronal inducers β-mercaptoethanol and glutathione, we examined its effect on neural induction of rat bone marrow mscs. materials and methods: in this experimental study, cells were treated in a medium containing 1mm cysteine for 24 hours prior to treatment with neu...
the incidence of traumatic brain injury (tbi) are annually increasing, developed tissue engineering methods could represent the definite remedies for patients with strongly injured central nervous system and have a great effect in the public healthcare cost. the current clinical treatments in tbi display several limitations. furthermore, several therapies, coming from neural tissue engineering ...
Adult neurogenesis, a concept emergent in the late 1990s, is the generation of new neurons in the adult brain. This process occurs thank to cells who have this proliferative feature, named as Neural Stem Cells (NSCs). Neural Stem Cells (NSCs) are primary progenitors who can generate the two neural types (neurons and glia). Classically it was assumed that NSCs are only present in the embryo, but...
Strategies of Schwann cell (SC) transplantation to regenerate the peripheral nerve injury involves many limitations. Stem cells can be used as alternative cell sources for differentiation into SCs. Given the high potential of neural crest-derived stem cells for the generation of multiple cell lineages, in this research, we considered whether olfactory ecto-mesenchymal stem cells (OE-MSCs) derive...
in addition to its antioxidant effect, vitamin e or α–tocopherol is suggested to enhance remyelination in the animal model of non-inflammatory demyelination. in this study, the possible proliferative effect of vitamin e on human- induced pluripotent stem cell-derived neural progenitors (hips-nps) and the underlying mechanisms were investigated in vitro. nps were induced from ips cells via 3 ste...
Traumatic brain injury (TBI) is defined as an external mechanical injury to the brain. Neuroinflammation plays a vital role in the pathophysiology of TBI. Microglia and astrocytes play a central role in the initiation and regulation of inflammation. Numerous pro-inflammatory mediators including cytokines, chemokines, reactive oxygen species (ROS) and nitric oxide (NO) released by microglia. In ...
Background & Aims: Throughout life, stem cells make new cells in various tissues. Bulge region of hair follicle indicated as sources of stem cells for along times but little studies done in vitro to characterize rat bulge hair follicle stem cells. Materials &Methods : In this study bulge cells of rat hair follicle were isolated and were cultured, then morphological features of differentia...
purpose: The aim of the present study is to understand if EBs can generate neural rosette upon co-culture with chick embryo somites. Materials and Methods: The mouse ES cells, line Royan Bl, were cultured in hanging drops to induce embryoid bodies (EBs) formation. Somites were isolated from the chick embryos and then embedded in alginate solution. Finally, alginate beads containing somites were...
هدف: دمیلیناسیون آکسونها در cns بزرگسالان جوان، مشخصه برجسته ms می باشد. دستگاه بینایی در بیش از 70 درصد بیماران متأثر می گردد. تا کنون درمان کاملی برای ms وجود نداشته است. رمیلیناسیون خودبخودی در ms روی می دهد، اگر چه ناکامل است. سلولهای بنیادی عصبی در مغز بزرگسالان ظرفیت فیزیولوژیک قابل توجهی را فراهم نموده اند. امکان مشارکت این ظرفیت بالقوه در پاسخ به القا آسیب دمیلینه کننده تجربی در ناحیه ک...
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