Neurofibromas are benign peripheral nerve sheath tumors seen arising both sporadically and in patients with neurofibromatosis syndromes. Commonly they of three types: localized, diffuse or plexiform. Pigmented neurofibromas very rare, accounting to <1% all reported. We present a case 64 year old woman Neurofibromatosis 1, large swelling on the right thigh. The mass was grossly pigmented micr...

The original version of this Article contained an error in the title where: " KANK1 inhibits cell growth by inducing apoptosis though regulating CXXC5 in human malignant peripheral nerve sheath tumors ". Now reads: " KANK1 inhibits cell growth by inducing apoptosis through regulating CXXC5 in human malignant peripheral nerve sheath tumors ". There were also typographical errors in the legends o...

Schwannomas are benign peripheral nerve sheath tumors that occur throughout the body. They may present as either solitary or multiple masses. They rarely occur in the nasal cavity. The diagnosis is often made only after histologic examination. Because these lesions are radioresistant, the preferred treatment is complete surgical excision. We present a new case of a schwannoma of the nasal cavity.

Schwannomas are benign nerve sheath tumors composed of Schwann cells, which normally produce the insulating myelin sheath covering the peripheral nerves. Common locations include the head, neck, mediastinum, and retroperitoneum. These tumors are usually asymptomatic until they become large and compress the surrounding tissues. Most schwannomas occur during the third and fourth decades of life, ...

Tumors arising from the supporting cells of peripheral nerve sheaths are relatively uncommon neoplasms, and as such many clinicians are unfamiliar with the details of their presentation, diagnosis and management. Further, little is known regarding the pathogenesis of these tumors, how they cause symptoms, and how to treat these symptoms. One classic symptom of peripheral nerve tumors is pain, h...

malignant peripheral nerve-sheath tumor (mpnst) is a high-grade malignant tumor of ecto-mesenchymal origin comprising approximately 10% of soft-tissue sarcomas. they tend to occur associated with neurofibromatosis or sporadically. here we report a mpnst at an extremely rare location and behavior causing disappearance of the entire kidney. patient evaluation included clinical, biochemical and ra...

We present an extremely unusual case of an extratemporal facial nerve malignant peripheral nerve sheath tumor (MPNST) arising from preexistent intratemporal neurofibroma, illustrating a difficulty in discriminating between perineural spread of the MPNST and the preexistent intratemporal neurofibroma on preoperative radiographic images. The most interesting point was that preoperative CT scan an...

palisaded encapsulated (solitary circumscribed) neuromas (pens) are relatively common intraoral neurogenic tumors, which occur most frequently on the hard palate. herein, we describe the clinicopathological characteristics of a palisaded encapsulated neuroma of the tongue. this tumor was an exophytic sessile mass measuring 0.3× 0.4 cm with rubbery consistency on the anterior one-third of the do...

malignant peripheral nerve sheath tumor (mpnst) is a rare malignant tumor that develops either from a preexisting neurofibroma or de novo. the cell of origin is believed to be the schwann cell and possibly other nerve sheath cells. in this report, we describe a rare case of mpnst that arise from the socket of second left maxillary molar that has been already extracted in a young man. he was ref...

Malignant peripheral nerve sheath tumor (MPNST) is a rare soft tissue sarcoma arising from neuroectoderm-derived cells comprising the outer coverings of peripheral nerves. Given the diverse cell types comprising the peripheral nerve sheath, both benign and malignant nerve sheath tumors display a wide range of histologic appearances. MPNST can arise either in association with proximal nerve trun...