background and objective: sensory neurons have critical role in improvement of functional outcome of any neuroprotective strategy. the herbal medicine nepeta menthoides has been reported to have anti-apoptotic effect on axotomized spinal motoneurons. in the present study, the putative neuroprotective effect of nepeta menthoides on the axotomized dorsal root ganglion sensory neurons in neonate r...

Resistance to chemotherapy and recurrence are major hurdles treating hormone receptor-negative breast cancer. The crude extract natural products obtained from medicinal plants believed be multitargeted possess less toxicity as compared synthetic compounds. aerial parts roots of Moricandia sinaica (Boiss.) Boiss were used prepare the extracts in solvents different polarities. Human cancer cell l...

BACKGROUND Premenstrual Syndrome (PMS) is a common problem in women. Zataria multiflora Boiss is a valuable plant. This herbal plant has been used in different conditions. OBJECTIVES The study was performed to investigate the effects of Zataria multiflora Boiss to control PMS symptoms. MATERIALS AND METHODS This study was a double-blinded, prospective randomized trial. The study population ...

UNLABELLED Ferula ovina (Boiss.) Boiss. is a traditional Iranian flavoring agent used as an ingredient of spices and condiments. METHODS AND RESULTS GC-MS analyses of F. ovina aerial parts' essential oil revealed the presence of a number of rare aromatic esters of monoterpenic alcohols. The structures of these esters were corroborated by synthesis, and one of them, bornyl 4-methoxybenzoate, t...

The essential oil composition of the aerial parts of Nepeta raphanorhiza is reported for the first time. Capillary GC-FID & GC-MS analysis of the essential oil led to the identification of 16 components accounting for 97.5% of the total oil. Sesquiterpene hydrocarbons dominated the oil composition accounting for 65.3 % followed by monoterpene hydrocarbons constituting 19.5 % of the total oil co...

BACKGROUND The efficacy and safety of Nepeta menthoides freeze-dried aqueous extract were assessed on the anxiety of patients suffering from depression. METHOD Patients received either N. menthoides formulation (400 mg/BID) or Sertraline (50 mg/BID) for 4 weeks. The Beck Anxiety Inventory (BAI) scales were used to assess the anxiety in two-week intervals (2(nd), 4(th), and 6(th) weeks). Folin...