Mitochondria can receive, integrate, and transmit a variety of signals to shape many biochemical activities of the cell. In the process of tumor onset and growth, mitochondria contribute to the capability of cells of escaping death insults, handling changes in ROS levels, rewiring metabolism, and reprograming gene expression. Therefore, mitochondria can tune the bioenergetic and anabolic needs ...

Lymphadenopathy is most commonly encountered problems in clinical practice. Various etiological factors can cause lymphadenopathy. Cytomorphological study of lymphadenopathy a window for diagnosis many disease processes. Aspiration cytology provides reliable, safe, rapid and economical method screening the patients with accuracy. It differentiate neoplastic from non-neoplastic lesions therefore...

The diagnosis of brain neoplasms has been facilitated by the emerging of high-quality imaging techniques, such as Magnetic Resonance Imaging (MRI), while the combination of several sequences from conventional and advanced protocols has increased the diagnostic information. Treatment planning and therapy follow-up require the detection of neoplastic and edematous tissue boundaries, a very time c...

INTRODUCTION High-risk human papilloma viruses play a main role in the development of cervical dysplasias and carcinomas. p16INK4a can be considered as a surrogate marker of active high-risk human papillomaviruses infection in dysplastic and neoplastic cells of the cervix. This study was aimed at determining the presence and level of pl6INK4a expression in inflammatory, preneoplastic and neopla...