background : meningitis is more common during the neonatal period than other periods of life and has a prevalence of one in 1000 live births. the similarity of its clinical manifestations with other infectious diseases makes it difficult to diagnose. the aim of the current study was to determine the relationship between age, sex, clinical signs and symptoms and laboratory test results of newbor...

The neonates are unique in several ways in comparison with older children and adults which render them highly susceptible to severe, sometimes life threatening dermatological disorders. The neonatal dermatological emergencies are a diagnostic and therapeutic challenge. A wide range of dermatoses such as infections, genodermatoses, metabolic disorders and vascular tumors may require emergency ca...

Adult AKR and C58 mice injected intramuscularly with murine sarcoma virus, Moloney isolate (M-MSV), developed high incidence of nonregressing local tumors. Histologically, these tumors revealed the typical pleomorphism of M-MSV sarcomas; in some cases, however, neoplastic tissue showed a nodular or diffuse growth of monomorphic myoblastlike cells, reminiscent of clonal aggregates. No depression...

cytomegalovirus (cmv) is a widespread pathogen that is found in milk, saliva, urine, cervical secretions, and semen fluid. it is supposed that cmv is a risk factor for breast cancer. the aim of this study was to determine the frequency of cmv among benign and malignant breast tumors. paraffin embedded breast carcinoma (n=24) and fibroadenoma (n=24) samples were collected from toos and firoozgar...

purpose: to report an extremely rare presentation of isolated orbital xanthogranuloma with no systemic disease, nor dermatologic manifestation. case report: the patient was a 45-year-old man complaining of a mass lesion in the superior and inferior eyelids of his right eye; the lesions had been enlarging slowly and painlessly since 5 years before. other examinations (including skin, heart, etc....

abstract objective tumors of the central nervous system constitute the largest group of solid neoplasms in children and are second only to leukemia in their overall frequency during childhood. the main purpose of the present study is to determine the incidence, age, sex, location and histological diagnosis of cns tumors in children, less than 15 years of age, in the mofid children's hospital, i...

intracranial hemangiopericytomas (hpc) are rare vascular tumors. they account for 0.4% of primary central nervous system tumors. hpc is more commonly located supratentorially and tends to occur in a younger age group, with average age at presentation of 38–42 years. the tumor was found throughout the entire cns, usually superficially and closely related to the meninges. moreover, they have a st...

Neonatal intravenous injection of gammaretroviral vectors (gamma-RVs) with an intact long terminal repeat (LTR) and an internal liver promoter can result in long-term expression in liver cells and correction of mucopolysaccharidosis. Some expression also occurs in blood cells and brain, which likely derives from the LTR, and may contribute to clinical efficacy. The goal of this project was to d...

The Copenhagen rat is completely resistant to mammary cancer induction by N-methyl-N-nitrosourea (MNU) when the carcinogen is administered during sexual development, a period when other strains of rats are normally susceptible to mammary gland carcinogenesis. Here we administered 30 mg/kg MNU i.p. to two groups of neonatal (2-3-day-old) Copenhagen rats. One group (group B, 18 animals) received ...