Introduction Interest in the activity of alkaline phosphatase of human leucocytes has grown rapidly with the increasing number of reports demonstrating significant shifts of activity in different clinical states. Leucocyte alkaline phosphatase (LAP), determined by cytochemical methods, is increased in bacterial infections of the adult, but to the best of the author's knowledge, there are no dat...

Viral infections during pregnancy may cause fetal or neonatal damage. Clinical intervention, which is required for certain viral infections, relies on laboratory tests performed during pregnancy and at the neonatal stage. This review describes traditional and advanced laboratory approaches and testing methods used for assessment of the six most significant viral infections during pregnancy: rub...

Cholestasis can occur in newborns due to infections. However, the manifestations of the underlying infections usually dominate the presentation. We present a 2-month-old infant who presented with jaundice and no fever or signs of systemic illness. Liver biopsy was suggestive of cholangitis. He was subsequently detected to have urinary tract infection with Klebsiella pneumoniae. The child was tr...