The functional components of vibrating mesh nebulizers are a piezoelectric ceramic with mounted on one side, reservoir, and driving circuit. material vibrates at specific intrinsic frequency, when the mechanical resonance frequency applied electrical signal match, vibration amplitude is greatest. In present study, nebulizing performances were tested respect to voltage after automatic tuning (AR...

Background Guidelines recommend that patients presenting with acute severe asthma with life-threatening features receive the necessary high doses of b2-agonists via the nebulized route.The SideStream Plus (SS+; Philips Respironics) is a breath-enhanced nebulizer designed to maximize respirable output, while minimizing treatment time [1]. Prior to the introduction of a new version of nebulizer, ...

In a clinical setting, the same aerosol generator is used to deliver therapeutics to infants and adults. Rational thought would suggest this is inappropriate. This investigation describes a static statistical model to determine the optimal particle diameter for largest therapeutic effect. Preliminary results confirm a difference between infants and adults.

Among inhaled asthma therapies, the present study aimed to identify factors for selecting the type of inhalation therapy for asthma. Three methods are used to deliver inhaled cromoglycate, and the airway deposition rate was evaluated using a cascade impactor with 3 dosage forms: dry powder (DP), pressurized metered dose inhaler (pMDI), and solution (jet- and mesh-types). The percentage of parti...

BACKGROUND At this time, several antibiotics have been investigated as possibilities for aerosol administration, but local therapy has been found to be more efficient in several diseases. MATERIALS AND METHODS The drugs linezolid (Zyvox), vancomycin (Voncon), and daptomycin (Cubicin) were tested with three jet nebulizers with seven different residual cups and different loadings. Moreover, thr...

OBJECTIVE To present a review of controversial issues related to the pharmacological management of the treatment of acute asthma in children. SOURCES Articles published in national and international scientific journals. Data were selected from Lilacs and Medline databases. SUMMARY OF THE FINDINGS The article was organized into topics, presenting aspects on which there is consensus regarding...

OBJECTIVES To evaluate the factors that affect nebulizer efficiency and to compare the relative cost effectiveness of nebulized medications used in the treatment of cystic fibrosis (CF), delivered by four types of disposable jet nebulizers that are widely used in hospitals. DESIGN The Hudson 1730 Updraft II, Baxter Misty-Neb, Marquest Whisper Jet (WJ), and Marquest Acorn II were evaluated in ...

Pressurized metered-dose inhalers (pMDIs) and nebulizers are routinely employed for aerosol delivery in mechanically ventilated patients. A significant proportion of the aerosol deposits in the ventilator circuit and artificial airway, thereby reducing the inhaled drug mass. Factors influencing aerosol delivery during mechanical ventilation differ from those in spontaneously breathing patients....

The use of nebulisers was assessed in four hospitals. Nebulisers were checked in use and medical and nursing staff were interviewed. All but one nebuliser was driven by 100% oxygen and only 3 of 111 interviewees preferred air for patients with hypercapnia. In 5 of 44 nebulisers in use, water was used as the dilutant. The calculated times for complete nebulisation of the solutions ranged from 3....