OBJECTIVE The New Delhi metallo-β-lactamase-1 (NDM-1) enzyme is a plasmid-encoded enzyme that inactivates carbapenem antibiotics. This study aims to ascertain if the modified Hodge test (MHT) has a role in screening for NDM-1 in Enterobacteriaceae with reduced carbapenem susceptibility. METHODS Over a period of one year, all Enterobacteriaceae isolates from all clinical specimens with reduced...

A carbapenem resistant Salmonella enterica serovar Senftenberg isolate BCH 2406 was isolated from a diarrheal child attending an outpatient unit of B.C. Roy Hospital in Kolkata, India. This isolate was positive for the bla NDM-1 in the PCR assay, which was confirmed by amplicon sequencing. Except for tetracycline, this isolate was resistant to all the tested antimicrobials. The bla NDM-1 was fo...

Treatment of neonatal sepsis has become a challenge with the emergence of carbapenemase-producing bacteria. This study documents the trend of carbapenem susceptibility in Enterobacteriaceae that caused septicaemia in neonates over a five year period (2007-2011) and the molecular characterisation of Enterobacteriaceae resistant to carbapenems and cephalosporins. Hundred and five Enterobacteriace...

Our purpose was to determine the influence of posture and breathing route on electromyographic (EMG) activities of nasal dilator (NDM) and genioglossus (GG) muscles during exercise. Nasal and oral airflow rates and EMG activities of the NDM and GG were recorded in 10 subjects at rest and during upright and supine incremental cycling exercise to exhaustion. EMG activities immediately before and ...

The presence of multidrug-resistant bacterial pathogens in the environment poses a serious threat to public health. The opportunistic Acinetobacter spp. are among the most prevalent causes of nosocomial infections. Here, we performed complete genome sequencing of the Acinetobacter calcoaceticus strain XM1570, which was originally cultivated from the sputum of a patient diagnosed with pneumonia ...

Naturalistic decision making (NDM) has become established as a methodological and theoretical perspective. It describes how practitioners actually make decisions in complex domains. However, NDM theories tend to focus on the human agents in the system. We extend the NDM perspective to include the technological agents in complex systems and introduce the dynamic model of situated cognition. We d...

New Delhi metallo-β-lactamase (NDM-1) has created a medical storm ever since it was first reported; as it is active on virtually all clinically used β-lactam antibiotics. NDM-1 rampancy worldwide is now considered a nightmare scenario, particularly due to its rapid dissemination. An underlying theme in the majority of recent studies is structural characterization as knowledge of the three-dimen...

Motivation – Understand decision making of mission critical personnel (e.g., police, firefighters, warriors, etc.) when life and limb are threatened. Research approach – Consilience (Wilson, 1999) was used to synthesize predator-prey dynamics, emotionprimed NDM and intuitive cognition to understand decision making under threat. Findings – Advances in ethology, cognitive and neurosciences do pro...

Carbapenems have been used for many years to treat severe nosocomial Enterobacteriaceae infections. The spread of resistance to these drugs among other bacterial families is an emerging problem worldwide, mostly caused by New Delhi metallo-β-lactamase (NDM-1). We screened for the prevalence of NDM-1-expressing enteric pathogens from hospitalized patients with acute diarrhea in Kolkata, India, a...

Stefan Heinz∗ and Harish Gopalan 1000 East University Avenue, Department of Mathematics, University of Wyoming, Laramie 82071, USA Abstract The existence of many different dynamic large eddy simulation (LES) methods leads to questions about the theoretical foundation of dynamic LES methods. It was shown recently that the use of stochastic analysis enables a theoretically well based systematic d...