Five new hydantoin alkaloids, named parazoanthines A-E (1-5), were isolated as the major constituents of the Mediterranean sea anemone Parazoanthus axinellae. Their structural elucidation was achieved through NMR spectroscopic and mass spectrometric analyses. The absolute configuration of the chiral compounds 1 and 4 was determined by comparison between experimental and TDDFT-calculated CD spec...

An important final step in development of an acute biotic ligand model for silver is to validate predictive capabilities of the biotic ligand model developed for fish and invertebrates. To accomplish this, eight natural waters, collected from across North America, were characterized with respect to ionic composition, pH, dissolved organic carbon, and sulfide. Tests were conducted with the clado...

PURPOSE To investigate the effects of a natural oil-based emulsion containing allantoin versus aqueous cream for preventing and managing radiation-induced skin reactions. METHODS AND MATERIALS A total of 174 patients were randomized and participated in the study. Patients received either cream 1 (the natural oil-based emulsion containing allantoin) or cream 2 (aqueous cream). Skin toxicity, p...

The endomyocardial biopsy (EMB) remains the gold standard mode of investigation for diagnosing many primary and secondary cardiac conditions. Through a percutaneous and transvenous route, tissue fragments are generally procured from the right ventricular septum, with very few complications. Widespread use of EMB followed the development of heart transplantation as a means to follow allograft re...

the side-effects of amitraz, buprofezin and propargite were studied on encarsia formosa (gahan)in the laboratory, using a life table response experiment and the iobc system for their toxicity. bioassayswere conducted by dipping bean leaves containing third instar nymphs of the whitefly trialeurodesvaporariorum (westwood), parasitized by e. formosa, in insecticide solutions or caging adult paras...

conclusions with regard to the potent antioxidant properties of silymarin, the neuroprotective effects of this natural compound suggested in the current study may in part be mediated through inhibition of oxidative stress. results exposure to acr reduced cell viability in pc12 cells. pre-treatment of cells with silymarin (100 µm) significantly reduced acr-induced toxicity. in addition, administ...

b a ckground: the efficacy of essential oil of chenopodium ambrosioides flowering aerial parts and its three main active ingredients was evaluated against blattella germanica male adults. m e t hods: composition of essential oil was determined by gc-ms. topical application bioassay was used to evalu- ate contact toxicity of essential oil and three main components. fumigant toxicity of essential...

Interferon-treated cells exhibited an increased susceptibility to the toxicity of several natural and synthetic double-stranded RNA molecules and to vaccinia virus, provided the latter was able to undergo replicative events. However, interferon-treated cells exhibited no enhanced susceptibility to several other toxic materials or to vaccinia virus that was unable to replicate; These findings su...

Ochratoxin A (OTA) is a natural contaminant that has displayed nephrotoxicity and hepatotoxicity in mammals. It contaminates a great variety of foodstuffs and threatens people's lives. The molecular mechanism of OTA-induced toxicity has been studied since 1965. Moreover, epigenetic mechanisms are also studied in OTA-induced toxicity. Additionally, the mode of OTA epigenetic research has been ad...

  Glyphosate, N–(phosphonomethyl) glycine, has been widely used to control agricultural weeds in the north of Iran. However, it is also supposed to have adverse effects on natural sturgeon population. The present study was undertaken to evaluate the acute toxicity of glyphosate to three different sturgeon species (Huso huso, Acipenser stellatus, and A. persicus) under laboratory conditions. Fis...