The metal-binding abilities of a wide variety of bioactive aminophosphonates, from the simple aminoethanephosphonic acids to the rather large macrocyclic polyaza derivatives, are discussed with special emphasis on a comparison of the analogous carboxylic acid and phosphonic acid systems. Examples are given of the biological importance of metal ion - aminophosphonate interactions in living syste...

BACKGROUND   Empathy dysfunction is one of the hallmarks of psychopathy, but it is also sometimes thought to characterise autism spectrum disorders (ASD). Individuals with either condition can appear uncaring towards others. This study set out to compare and contrast directly boys with psychopathic tendencies and boys with ASD on tasks assessing aspects of affective empathy and cognitive perspe...

We formulate the problem of nonprojective dependency parsing as a polynomial-sized integer linear program. Our formulation is able to handle non-local output features in an efficient manner; not only is it compatible with prior knowledge encoded as hard constraints, it can also learn soft constraints from data. In particular, our model is able to learn correlations among neighboring arcs (sibli...