To ensure targeting of apoferritin nanocarrier with encapsulated doxorubicin drug, we used a peptide linker based on a protein G with N-terminus affinity towards Fc region of antibodies. To connect the peptide to the surface of apoferritin, the C-terminus of peptide was made of cysteine with affinity to gold. The surface of apoferritin with encapsulated doxorubicin (APODOX) was coated either wi...

We report the development of a robust interface for off-line coupling of nano liquid chromatography (LC) to matrix-assisted laser desorption/ionisation-mass spectrometry (MALDI-MS) and its application to the analysis of proteolytic digests of proteins, both isolated and in mixtures. The interface makes use of prestructured MALDI sample supports to concentrate the effluent to a small sample plat...

the present paper investigates the potential application of graphene sheets with attached nanoparticles as resonant sensors by introducing a nonlocal shear deformation plate model. to take into account an elastic connection between the nanoplate and the attached nanoparticle, the nanoparticle is considered as a mass-spring system. then, a combination of pseudo-spectral and integral quadrature m...

We propose to use a buckled plate as qubit, where double-well potential is mechanically produced by pushing the from both sides. The right and left positions of are assigned be quantum states $|0\ensuremath{\rangle}$ $|1\ensuremath{\rangle}$. not gate executed changing buckling force acting on plate, while Pauli-$Z$ phase-shift applying an electric field. A two-qubit materialized with electrost...

We demonstrate nano-fabrication of high-aspect ratio and high-spatial frequency diffractive X-ray optics with high uniformity for use in a laser-plasma-based compact water-window X-ray microscope. The structures are fabricated on 50 nm thin Si3N4-membranes using a three-layer resist scheme and 30 keV e-beam lithography in combination with reactive ion etching and nickel electroplating. The proc...

We discuss subwavelength-scale semiconductor metal-optic resonators placed on the metal substrate with various top metal plate sizes. Albeit with large optical losses, addition of metal layers converts a leaky semiconductor nano-block into a highly-confined optical cavity. Optically pumped lasing action is observed with the extended top metal layer that can significantly suppress the radiation ...

nano-cus powders were synthesized with chemical solution method. xrd and sem and spectrophotometry were used for characterization of the cus powders. xrd analysis indicated that tetragonal cus was the main phase with particle size of 16.2nm and little cu2s phase was present. scanning electron microscopy (sem) analysis revealed that powder was plate like and had very little aspect ratio in morph...

Microchannel plate (MCP) as a key part is a kind of electron multiplied device applied in many scientific fields. Oxide thin films such as zinc oxide doped with aluminum oxide (ZnO:Al2O3) as conductive layer and pure aluminum oxide (Al2O3) as secondary electron emission (SEE) layer were prepared in the pores of MCP via atomic layer deposition (ALD) which is a method that can precisely control t...