1. Three experiments were conducted to determine the flow of nitrogen through the rumen and abomasum when cows, steers and lambs were totally nourished on volatile fatty acids infused into the rumen. 2. In two dairy cows (650-700 kg) and two large steers (370-405 kg) the daily flow of non-ammonia-N (NAN) from the rumen was 50.7 and 58 mg/kg live weight (W)0.75 respectively. 3. The flows of NAN ...

C-reactive protein (CRP), an acute-phase protein and newly recognized indicator of cardiovascular risk, may have direct actions on the vascular wall. Previous studies suggest that CRP is a vasodilator that activates smooth muscle K(+) channels. We examined the reported vasoactive properties of CRP and further explored its mechanisms of action. CRP decreased blood pressure in rats and increased ...

Previous studies demonstrated methane generation in aerobic cells. Our aims were to investigate the methanogenic features of sodium azide (NaN(3))-induced chemical hypoxia in the whole animal and to study the effects of l-α-glycerylphosphorylcholine (GPC) on endogenous methane production and inflammatory events as indicators of a NaN(3)-elicited mitochondrial dysfunction. Group 1 of Sprague-Daw...

Low voltage-activated (LVA) T-type Ca(2+) (I(Ca)T) and NaN/Nav1.9 currents regulate DRG neurons by setting the threshold for the action potential. Although alterations in these channels have been implicated in a variety of pathological pain states, their roles in processing sensory information remain poorly understood. Here, we carried out a detailed characterization of LVA currents in DRG neur...

consequences of unprotected intercourse or contraceptive failure: It is estimated that among Australian teenagers, one abortion occurs for every teenage birth,7 and that the number of teenagers having abortions each year has more than doubled since 1971.8 Young people in Australia are exposed to two potentially conflicting discourses regarding sexual health: one focusing on safer sex and the ot...

Deferasirox is an orally effective iron (Fe) chelator currently used for the treatment of iron-overload disease and has been implemented as an alternative to the gold standard chelator, desferrioxamine (DFO). Earlier studies demonstrated that DFO exhibits anticancer activity due to its ability to deplete cancer cells of iron. In this investigation, we examined the in vitro and in vivo activity ...

The dataset to be analyzed is the dataset of Reddit submissions suggested in lecture. (http://snap.stanford.edu/data/webReddit.html). In this dataset, there are 132,308 entries for analysis. Of these entries, however, there are only 16,736 unique images, and on average, each was resubmitted approximately 7.9 times. The timespan across which these Reddit submissions were made is July 2008 to Jan...

Human embryonic stem cells (hESCs) are routinely cultured on fibroblast feeder layers or in fibroblast-conditioned medium (CM). Bone morphogenetic proteins (BMPs) have previously been shown to induce hESC differentiation, in apparent contrast to mouse embryonic stem (ES) cells, in which BMP4 synergizes with leukemia inhibitory factor (LIF) to maintain self-renewal. Here we demonstrate that hESC...

Author′s Affiliations: Department of Radiation Oncology, Department of Nasopharyngeal Carcinoma, Sun Yat-sen University Cancer Center; State Key Laboratory of Oncology in South China; Collaborative Innovation Center for Cancer Medicine, Guangzhou, Guangdong 510060, P. R. China. Corresponding Author: Chao-Nan Qian, Department of Nasopharyngeal Carcinoma, Sun Yat-sen University Cancer Center, Gua...

Qing-Jian Han, Nan-Nan Gao, Guo-Qiang Ma, Zhen-Ning Zhang, Wen-Hui Yu, Jing Pan, Qiong Wang, Xu Zhang and Lan Bao* State Key Laboratory of Cell Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China Institute of Neuroscience and State Key Laboratory of Neuroscience, Shanghai Institutes for Biological ...