Mitochondrial DNAs (mtDNAs) has been frequently used as genetic markers for the population genetic studies. In this study we used chum salmon (Oncorhynchus keta) from Korea, Japan andAmerica, and compared their mitochondrial NADH dehydrogenase subunit 3 (ND3) genes by DNA sequence analysis. Sequence variation was studied in the ND3 among total 11 individuals from three populations. The ND3 gene...

A heteroplasmic G-to-A transition at nucleotide pair (np) 14459 within the mitochondrial DNA (mtDNA)-encoded NADH dehydrogenase subunit 6 (ND6) gene has been identified as the cause of Leber hereditary optic neuropathy (LHON) and/or pediatric-onset dystonia in three unrelated families. This ND6 np 14459 mutation changes a moderately conserved alanine to a valine at amino acid position 72 of the...

To the Editor: Alveolar echinoco-ccosis (AE) caused by Echinococcus multilocularis is one of the most important emerging zoonosis in Europe. The fatality rate is >90% in untreated patients (1). In Europe, the distribution range of the zoonotic tapeworm E. multilocularis has expanded over the last few decades, and the parasite attracts increasing awareness as a public health issue (2–5). In 2003...

L-Lactaldehyde is a branching point in the metabolic pathway of L-fucose and L-rhamnose utilization. Under aerobic conditions, L-lactaldehyde is oxidized to L-lactate by the enzyme lactaldehyde dehydrogenase, while under anaerobic conditions, L-lactaldehyde is reduced to L-1,2-propanediol by the enzyme propanediol oxidoreductase. Aerobic growth on either of the methyl pentoses induces a lactald...

The western bean cutworm, Striacosta albicosta (Smith) (Lepidoptera: Noctuidae), is a pest of both corn and dry bean crops. At the beginning of the 21st century, the species began to extend its range out of the Great Plains, eastward through the Corn Belt. This rapid range expansion is remarkable because the species distribution had been stable for at least the previous half century, despite th...

Antibodies have been raised against synthetic peptides corresponding to several computer-predicted epitopes of three mtDNA-encoded subunits, ND4, ND5 and ND6, of the human respiratory chain NADH dehydrogenase (Complex I). Antibodies were characterized by a sensitive immunoblotting assay using proteins from human skeletal muscle mitochondria and by immunoprecipitation of radio-labeled HeLa cell ...

The 30 living species of armadillos, anteaters, and sloths (Mammalia: Xenarthra) represent one of the three major clades of placentals. Armadillos (Cingulata: Dasypodidae) are the earliest and most speciose xenarthran lineage with 21 described species. The question of their tricky phylogeny was here studied by adding two mitochondrial genes (NADH dehydrogenase subunit 1 [ND1] and 12S ribosomal ...

The Nearctic leafhopper genus Errhomus Oman (Hemiptera: Cicadellidae) exhibits high host-plant selectivity and female brachyptery, which may limit gene ßow. Two subgenera, Errhomus (Errhomus) and Errhomus (Erronus), are recognized based on morphological and behavioral differences.WeusedmitochondrialDNA sequencing to elucidate the phylogenetic relationships amongmembers of the subgenus Errhomus ...

The molecular mechanism of the anthracycline-dependent development of cardiotoxicity is still far from being clear. However, it is generally accepted, that mitochondria play a significant role in triggering this organ specific injury. The results presented in this study demonstrate that, in contrast to liver mitochondria, isolated heart mitochondria shuttle single electrons to adriamycin, givin...

I. NADH dehydrogenase (EC 1.6.99.3) has been purified from the strictly anaerobic rumen bacterium Peptostreptococcus elsdenii. The purified protein is specific for NADH as electron donor; it can use 2,6-dichlorophenolindophenol (DCIP), cytochrome c, KzFe(CN)6 or flavodoxin as electron acceptor. It has a molecular weight of about 63 ooo. The absorption spectrum shows maxima at 475, 375, 356, 318...