Net Mg(2+) absorption from the rumen is mainly mediated by a transcellular pathway, with the greater part (62%) being electrically silent. To investigate this component of Mg(2+) transport, experiments were performed with isolated ruminal epithelial cells (REC). Using the fluorescent indicators mag-fura 2, sodium-binding benzofuran isophthalate, and 2', 7'-bis(2-carboxyethyl)-5(6)-carboxyfluore...

3 PharmaEast GmbH, Berlin, Germany There is increasing evidence indicating that certain drugs evoke adverse drug effects that depend on the gender of patients. Elucidation of gender-effect of various drugs by means of preclinical trials is an important field of pharmacology. The chloriuretic and natriuretic effect of valproates (VPA) had not been investigated earlier, so the aim of the present ...

This study investigated the role of the Na-H exchanger (NHE) on angiotensin II (Ang II)–induced activation of Na-dependent Mg transport in vascular smooth muscle cells (VSMCs) from Wistar-Kyoto rats (WKY; n520) and spontaneously hypertensive rats (SHR; n520). Intracellular free concentrations of Mg ([Mg]i) and Na 1 ([Na]i) and intracellular pH (pHi) were measured with the specific fluorescent p...

Two metabolism trials were conducted to determine the effect of altering dietary Na and K on Mg availability. Three dietary treatments (normal K-normal Na, high K-normal Na and high K-high Na) were imposed upon nine crossbred wether lambs in a randomized block design. Each trial consisted of a 5-d diet adjustment, a 10-d preliminary period and a 5-d collection of feed, feces and urine. Increasi...

Since monosodium urate (NaU) may play an important etiologic role in the formation of renal stones containing Ca in patients with hyperuricosuria, the current studies were undertaken to define some of the physiocochemical factors which determine the formation of NaU. In solutions containing Na, uric acid was rapidly transformed to NaU at pH greater than 6. The results indicated that NaU, and no...

To elucidate the purpose of butterfly puddling, we measured the amounts of Na+, K+, Ca2+, and Mg2+ that were absorbed or excreted during puddling by male Japanese Papilio butterflies through a urine test. All of the butterflies that sipped water with a Na+ concentration of 13 mM absorbed Na+ and excreted K+, although certain butterflies that sipped solutions with high concentrations of Na+ excr...

To provide novel information on psittacine diets, we analyzed the texture, crude protein, crude fat, Ca, P (total), Mg, K, Na, S, Cu, Fe, and Zn concentrations of crop contents from 10 free-living scarlet macaw (Ara macao) chicks from lowland forests of southeastern Peru. We compared our results with nutrient concentrations of known wild parrot foods and published psittacine dietary recommendat...