Recent developments in spatial proteomics have paved the way for retrospective in situ mass spectrometry (MS) analyses of formalin-fixed paraffin-embedded clinical tissue samples. This type of analysis is commonly referred to as matrix-assisted laser desorption/ionization (MALDI) imaging. Recently, formalin-fixed paraffin-embedded MALDI imaging analyses were augmented to allow in situ analyses ...

The BRAF T1799A mutation is a heterozygous point mutation and its reported prevalence in papillary thyroid carcinoma (PTC) has varied from 29 to 83%, with an overall mean of 44%. In Korea, the reported mutation rate reached 83% in PTC and 52% in micropapillary carcinoma. We hypothesized that the differences in prevalence may be influenced by the methods of mutation analysis, the sizes of tumor ...

in this study 152 bacterial strains were isolated from the contaminated oils in the southwest of iran. hemolysis was used as a criterion for the primary  isolation of biosurfactant producing-bacteria. fifty five strains had haemolytic activity , among them tweleve strains were good biosurfactant producers by measuring surface tension and emulsification activity.two microorganism showed the high...

Background: Mancozeb, (ethylene-bis-dithiocarbamate), is an important fungicide useful against a wide range of fungus affecting ornamental plants, crops, and fruits. We aimed to evaluate the changes in olfactory mucosa due mancozeb toxicity and, if cytokine active, IL-6 immunoactivity. Material Method: In experimental group, (500 mg/kg) was administered with inhalation 10 male Wistar Albino rat...

BACKGROUND The determination of NRAS and BRAF mutation status is a major requirement in the treatment of patients with metastatic melanoma. Mutation specific antibodies against NRAS(Q61R) and BRAF(V600E) proteins could offer additional data on tumor heterogeneity. The specificity and sensitivity of NRAS(Q61R) immunohistochemistry have recently been reported excellent. We aimed to determine the ...