نتایج جستجو برای: n alanine para styrene sulfonamide

تعداد نتایج: 1275851  

Journal: :Tropical Journal of Pharmaceutical Research 2022


 Purpose: To determine the effect of glutathione (GSH) suppressors styrene oxide (SO) and diethyl maleate (DEM) on hepatic expression cytochrome P450 family 1 (Cyp1) isoforms that are related to carcinogenesis including Cyp1a1, Cyp1a2, Cyp1b1.
 Methods: Seven-week-old ICR mice were intraperitoneally injected with SO (150 300 mg/kg/day), DEM (175 350 or N-acetylcysteine (NAC; 600 mg/k...

2008
Radia Bouasla Malika Berredjem Nour-Eddine Aouf Carole Barbey

The title compound, C(9)H(12)N(2)O(2)S, is a useful precursor of a variety of modified sulfonamide mol-ecules. Due to the importance of these mol-ecules in biological systems (antibacterials, antidepressants and many other applications), there is a growing inter-est in the discovery of new biologically active compounds. In the title compound, the mol-ecules are linked by N-H⋯O inter-molecular h...

Journal: :Acta biochimica Polonica 2004
Dawid Siodłak Barbara Rzeszotarska Małgorzata A Broda

Ab initio/DFT analysis of the conformational properties of free Ac-Ala-NMe(2) (N-acetyl-L-alanine-N',N'-dimethylamide) in terms of the N-H.O, N-H.N, C-H.O hydrogen bonds and C(delta+) = O(delta-) dipole attractions was performed. The Ala residue combined with the C-terminal tertiary amide prefers an extended conformation and that characteristic of the (i + 1)th position of the betaVIb turn. The...

Journal: :The Journal of the Society of Chemical Industry, Japan 1964

Journal: :Cancer research 1986
M L Veigl W D Sedwick J Niedel M E Branch

The naphthalene sulfonamide calmodulin antagonists, N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide and N-(4-aminobutyl)-5-chloro-2-naphthalenesulfonamide, both induce limited myeloid differentiation of the human promyelocytic cell line, HL-60. In addition, these inhibitors augment the differentiation observed when HL-60 cells are induced with retinoic acid, dimethyl sulfoxide, or dibutyryl ...

Journal: :Dalton transactions 2015
Fanny Bonnet Hellen E Dyer Yassine El Kinani Carin Dietz Pascal Roussel Marc Bria Marc Visseaux Philippe Zinck Philip Mountford

New bis(phenolate)amine-supported neodymium borohydride complexes and their previously reported samarium analogues were tested as catalysts for the polymerisation of styrene and isoprene. Reaction of Na2O2N(L) (L = py, OMe, NMe2) with Nd(BH4)3(THF)3 afforded the borohydride complexes Nd(O2N(L))(BH4)(THF) (L = py (1-Nd), OMe (2-Nd), NMe2 (3-Nd)). Complex 1-Nd has shown a propensity to form pheno...

2017
K. Shakuntala S. Naveen N. K. Lokanath P. A. Suchetan

The crystal structures of three isomeric compounds of formula C14H13Cl2NO2S, namely 3,5-di-chloro-N-(2,3-di-methyl-phen-yl)-benzene-sulfonamide (I), 3,5-di-chloro-N-(2,6-di-methyl-phen-yl)benzene-sulfonamide (II) and 3,5-di-chloro-N-(3,5-di-methyl-phen-yl)benzene-sulfonamide (III) are described. The mol-ecules of all the three compounds are U-shaped with the two aromatic rings inclined at 41.3 ...

Journal: :The Journal of biological chemistry 1986
B H Stock J Schreiber C Guenat R P Mason J R Bend T E Eling

We have proposed, using styrene as a model, a new mechanism for the formation of glutathione conjugates that is independent of epoxide formation but dependent on the oxidation of glutathione to a thiyl radical by peroxidases such as prostaglandin H synthase or horseradish peroxidase. The thiyl radical reacts with styrene to yield a carbon-centered radical which subsequently reacts with molecula...

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