Inflammatory myopathies are a heterogeneous group of acquired systemic diseases, which include dermatomyositis (DM), polymyositis (PM), necrotising myopathy (NM) and inclusion body myositis (IBM). All four disease entities share certain clinical characteristics, such as progressive muscle weakness and elevated muscle enzymes. Other characteristic-associated features such as skin involvement in ...

The discovery of unique autoantibodies has informed and altered our approach to the diagnosis and management of the inflammatory myopathies. This study reports the initial clinical experience of use of the Extended Myositis Antibody (EMA) panel in the largest university teaching hospital in Ireland. We conducted a retrospective review of all patients who had serum samples tested for myositis sp...

We report a 9-year-old Japanese girl who presented with muscle weakness and elevated serum levels of muscle-derived enzymes following mycoplasma infection. Rhabdomyolysis or myositis was suggested by magnetic resonance imaging and repeated four times within 4 years. Each episode developed following respiratory infection and spontaneously recovered. The diagnosis of Sjögren’s syndrome was made b...

Dengue is an acute mosquito-borne infection caused by dengue viruses from the genus flavivirus. Although viral myositis is common, myositis caused by dengue virus is not commonly reported. We present a case of an 18 year old female with serologically confirmed dengue fever presenting with severe myalgia and lower limb weakness. Twenty fold elevation of serum creatinine kinase level was noted. S...

Inclusion-body myositis is the most frequent and disabling myopathy seen in patients over 50 years of age. The distinct clinical features that lead to correct diagnosis and inclusion-body myositis mimics are highlighted. Inclusionbody myositis has a complex pathogenesis in which autoimmune and inflammatory features coexist with elements of degeneration and abundant accumulations of various stre...

Tropical myositis is a condition characterised by the presence of suppurative lesions within skeletal muscles. There has been little agreement regarding the terminology various names used include purulent tropical myositis, tropical pyornyositis, tropical skeletal muscle abscess, spontaneous bacterial myositis or epidemic abscess. The earliest anecdotal reports of patients presenting both skele...

Idiopathic orbital myositis is an unspecific isolated inflammation of extra-ocular muscles. It is uncommon in children, especially in infants, and is a source of real diagnosis problems. We report the case of a 22 months old infant who was admitted for a sudden swollen eyelid with ptosis and painful bilateral eyes exophtalmos. The orbital computed tomography revealed bilateral and diffuse hyper...

We report an infant case of rotavirus myositis, a rare complication of rotavirus infection. Complement levels of the patient were normal when serum creatine kinase (CK) level was at its peak and then decreased when the CK level became normalized. In a previous case report of rotavirus myositis, transient decrease of serum albumin, immunoglobulin, and complement levels was reported. The authors ...

Parvovirus B19 infection is often asymptomatic, but clinical expressions may include transient aplastic crisis, erythema infectiosum, non-immune hydrops fetalis, and chronic red cell aplasia. This virus has also been associated with rheumatoid arthritis and other autoimmune connective tissue diseases; however, we could not identify any acute adult myositis case developed after a Parvovirus B19 ...