Dear Sir, the recent issue of Nuclear Medicine Review published an interesting study by Gholamrezanezhad et al. regarding rate dependent left bundle branch block and its effect on myocardial perfusion SPECT [1]. They reported four cases with rate dependent LBBB during exercise stress for myocardial perfusion imaging. Myocardial perfusion SPECT imaging showed no evidence of reversible perfusion ...

Coronary artery disease is the leading cause of death in the Western society. The use of non-invasive cardiac imaging in combination with exercise or pharmacological stress has become a cornerstone for the objective assessment and subsequent treatment strategy of coronary artery disease. This results in an improved life expectancy and cost savings. Echocardiography and myocardial perfusion scin...

UNLABELLED Coronary stent implantation is an increasingly accepted revascularization method. The 20%-30% restenosis rate during the first 6 mo requires a close follow-up of the patients. Since there is very little data available defining the role of perfusion scintigraphy in the management of this population, the aim of this study was to assess the diagnostic performance of stress myocardial pe...

Heart failure is increasing worldwide at epidemic proportions, resulting in considerable disability, mortality, and increase in healthcare costs. Gated myocardial perfusion single photon emission computed tomography or PET imaging is the most prominent imaging modality capable of providing information on global and regional ventricular function, the presence of intraventricular synchronism, myo...

BACKGROUND The extent and severity of ischemia on myocardial perfusion scintigraphy (MPS) is commonly used to risk-stratify patients with coronary artery disease. Estimation of ischemic burden by cardiovascular magnetic resonance (CMR) with conventional 2-dimensional myocardial perfusion methods is limited by incomplete cardiac coverage. More recently developed 3-dimensional (3D) myocardial per...

Background—We investigated the hemodynamic and coronary vasodilatory effects of CGS-21680, a potent selective adenosine A2A agonist, as well as its potential use as a new stress modality in combination with perfusion scintigraphy. Methods and Results—A stenosis of the left anterior descending coronary artery (LAD) was produced in dogs to reduce the reactive hyperemic response to ,20%. Adenosine...

introduction: leptin, secreted from adipose tissue may have some correlation with coronary artery disease according to some reports in literature. the mean concentration of plasma leptin in patients with normal and abnormal myocardial perfusion imaging (mpi) and relation of leptin levels, independently to abnormality in mpi after correction for body mass index (bmi) was evaluated. methods: as a...

The purpose of this study was to validate whether dipyridamole stress ultrasonic tissue characterization with cyclic variation of integrated backscatter (CVIBS) compared with dipyridamole stress echocardiography and dipyridamole stress Tc99m-MIBI SPECT myocardial perfusion scintigraphy could predict myocardial ischemia in patients with chronic coronary artery disease. Twenty patients (16 M, 4 F...

In this study, we have compared scintigraphic and echocardiographic data in order to investigate whether increased septal perfusion represents asymmetrical septal hypertrophy (ASH), which is a symptom followed in the scintigraphy of myocardial perfusion. The study consists of a total of 186 patients (120 females and 66 males with an average age of 59.45 ± 11.54 years) who had normal myocardial ...

1 Health Services Research Unit, Institute of Applied Health Sciences, University of Aberdeen, UK 2 Health Economics Research Unit, Institute of Applied Health Sciences, University of Aberdeen, UK 3 Department of Public Health, Institute of Applied Health Sciences, University of Aberdeen, UK 4 Nuclear Medicine Physics, Department of Bio-Medical Physics and Bio-Engineering, University of Aberdee...