OBJECTIVE The aim of this study was to determine the safety and efficacy of adenosine Tc99m sestamibi myocardial perfusion study under controlled conditions and to correlate the adenosine Tc99m sestamibi perfusion defects and the coronary angiography in patients investigated for coronary artery disease. METHODS This prospective study included 122 consecutive patients who underwent adenosine T...

Background. Heart failure is a major cause of morbidity and death in patients with coronary artery disease (CAD). The aim of this study was to define the incidence and predictors of heart failure during long-term follow-up in patients with suspected CAD referred for stress myocardial perfusion imaging. Methods and Results. We studied 787 patients (mean age, 57 12 years; 470 men) with suspected ...

PURPOSE To compare myocardial enhancement during first-pass myocardial perfusion imaging at 3.0 Tesla (T) and 1.5T. MATERIALS AND METHODS First-pass myocardial perfusion imaging was performed on twelve normal subjects at 3T and 1.5T using an interleaved notched saturation recovery gradient echo pulse sequence. Subjects received either 0.10 mmol/kg for both scans (group 1), 0.075 mmol/kg for b...

A 61-year-old man with chronic chest pain was referred for a myocardial perfusion scan. Following dipyridamole infusion, 99mTc-MIBI was injected and the reconstructed images showed decreased activity in the anteroseptal wall, which prompted the supervising physician to review the cinematic data. Reviewing the cinematic images revealed abnormal 99mTc-MIBI uptake by the ribs, clavicles, and more ...

This study evaluated the relationship between the location of the most severe coronary artery stenosis and the subsequent acute myocardial infarction (AMI). Methods: Of 1590 patients who were admitted with a diagnosis of AMI, we identified 44 patients who had undergone previous myocardial perfusion SPECT. Thirty-one of these patients also had previous coronary angiography. The relationshi...

the relationship between qt dispersion and myocardial ischemia is still controversial. therefore, we aimed to investigate the relationship between qtd and the severity and extent of myocardial ischemia. in this cross-sectional study, 141 patients having symptoms of cad who referred to our medical center during 2009-2010, and were examined with myocardial isotope scan and ecg, were enrolled. bas...

introduction:patients with the coronary slow flow phenomenon (scf) frequently experience angina episodes. the purpose of this study was to determine efficacy of nicorandil in myocardial perfusion in patients with scf. methods: twenty patients (50.85 ± 12.96 y) with scf were studied.  we evaluate coronary slow flow according to protracted thrombolysis in myocardial infarction (timi) frame count....

objective(s): radiation therapy for breast cancer can induce myocardial capillary injury and increase cardiovascular morbidity and mortality. a prospective cohort was conducted to study the prevalence of myocardial perfusion abnormalities following radiation therapy of left-sided breast cancer patients as compared to those with right–sided cancer. methods: to minimize potential confounding fact...

to make an accurate estimation of the uptake of radioactivity in an organ using the conjugate view method, corrections of physical factors, such as background activity, scatter, and attenuation are needed. the aim of this study was to evaluate the accuracy of four different methods for background correction in activity quantification of the heart in myocardial perfusion scans. the organ activit...