نتایج جستجو برای: myeloid derived suppressor cell
تعداد نتایج: 2090781 فیلتر نتایج به سال:
OBJECTIVES Myeloid-derived suppressor cells contribute to the immunosuppressive microenvironment during tumor development and limit the efficacy of cancer immunotherapy. Identifying myeloid-derived suppressor cells and associated factors is the first step in creating strategies to reverse the suppressive effects of these cells on the immune system. METHODS To induce lung cancer, we administer...
Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of cells that expands during cancer, inflammation and infection, and together with regulatory T cells (Tregs) have a remarkable ability to suppress immune responses. The phenotype of MDSCs differs in humans and mice, and the exact mechanisms of their suppressive function are still controversially discussed. Limited data are...
Myeloid derived suppressor cells (MDSCs) are defined in mice on the basis of CD11b and Gr-1 marker expression and the functional ability to inhibit T lymphocyte activation. Nevertheless the term 'heterogeneous' remains the first, informal feature commonly attributed to this population. It is clear that CD11b(+)Gr-1(+) cells are part of a myeloid macropopulation, which comprises at least two sub...
Citation: Tian X, Ma J, Wang T, Tian J, Zhang Y, Mao L, Xu H and Wang S (2018) Long Non-Coding RNA HOXA Transcript Antisense RNA MyeloidSpecific 1–HOXA1 Axis Downregulates the Immunosuppressive Activity of Myeloid-Derived Suppressor Cells in Lung Cancer. Front. Immunol. 9:473. doi: 10.3389/fimmu.2018.00473 long non-coding rna hOXa Transcript antisense rna Myeloid-specific 1–hOXa1 axis Downregul...
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